A benchtop induction-based AC magnetometer for a fast characterization of magnetic nanoparticles
In this study, we report a development of a benchtop induction-based AC magnetometer to realize a simple, wideband, and sensitive AC magnetometer for bio-sensing applications and characterization of magnetic nanoparticles (MNPs). We investigate the inductance and parasitic capacitance of six differe...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English English |
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Institute of Physics
2022
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| Online Access: | http://umpir.ump.edu.my/id/eprint/42682/1/A%20benchtop%20induction-based%20AC%20magnetometer.pdf http://umpir.ump.edu.my/id/eprint/42682/2/A%20benchtop%20induction-based%20AC%20magnetometer%20for%20a%20fast%20characterization%20of%20magnetic%20nanoparticles_ABS.pdf |
| _version_ | 1824451636183957504 |
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| author | Mohd Mawardi, Saari Mohd Herwan, Sulaiman Hamzah, Ahmad Nurul Akmal, Che Lah Sakai, Kenji Kiwa, Toshihiko Tsukada, Keiji |
| author_facet | Mohd Mawardi, Saari Mohd Herwan, Sulaiman Hamzah, Ahmad Nurul Akmal, Che Lah Sakai, Kenji Kiwa, Toshihiko Tsukada, Keiji |
| author_sort | Mohd Mawardi, Saari |
| collection | UMP |
| description | In this study, we report a development of a benchtop induction-based AC magnetometer to realize a simple, wideband, and sensitive AC magnetometer for bio-sensing applications and characterization of magnetic nanoparticles (MNPs). We investigate the inductance and parasitic capacitance of six different pickup coil geometries and compare their sensitivity and usable frequency range. In the pickup coil design, the number of turns and coil section separation are varied from 200 to 400 turns, and 1 to 4 sections, respectively. We find that the usable frequency range is greatly affected by the pickup coil's inductance due to the self-resonance phenomena compared to their parasitic capacitance. A low noise instrument amplifier circuit (AD8429, Analog Devices, USA) was integrated and fabricated on a printed circuit board to amplify the weak signal from the pickup coil. We also implement a generalized Goertzel algorithm to achieve fast signal amplitude and phase extractions at a frequency. The developed magnetometer shows a sensitivity of 10-8 Am2/Hz at 6 Hz and a frequency range of up to 158 kHz. Using the developed AC magnetometer, we demonstrate the viscosity effect on the frequency response of thermally blocked, single-core nanoparticles (SHP30, Ocean Nanotech, USA) in glycerol solutions. The excitation frequency is swept from 5 Hz to 158 kHz at a field amplitude of 0.55 mTpp within the acquisition time of 5 min (51 points). As a result, the viscosity change is confirmed by the peak shifting in the imaginary magnetization curve towards lower frequency values when the wt/V% of the glycerol solution is increased. The hydrodynamic size and the average anisotropy energy ratio σ are estimated to be 60.6 nm and 25, respectively, from the complex AC magnetization. It can be expected that the developed AC magnetometer can be a valuable tool in providing a fast and reliable assessment of MNPs for bio-sensing applications. |
| first_indexed | 2025-02-19T02:37:46Z |
| format | Article |
| id | UMPir42682 |
| institution | Universiti Malaysia Pahang |
| language | English English |
| last_indexed | 2025-02-19T02:37:46Z |
| publishDate | 2022 |
| publisher | Institute of Physics |
| record_format | dspace |
| spelling | UMPir426822025-01-07T03:50:52Z http://umpir.ump.edu.my/id/eprint/42682/ A benchtop induction-based AC magnetometer for a fast characterization of magnetic nanoparticles Mohd Mawardi, Saari Mohd Herwan, Sulaiman Hamzah, Ahmad Nurul Akmal, Che Lah Sakai, Kenji Kiwa, Toshihiko Tsukada, Keiji T Technology (General) TA Engineering (General). Civil engineering (General) TJ Mechanical engineering and machinery TK Electrical engineering. Electronics Nuclear engineering TS Manufactures In this study, we report a development of a benchtop induction-based AC magnetometer to realize a simple, wideband, and sensitive AC magnetometer for bio-sensing applications and characterization of magnetic nanoparticles (MNPs). We investigate the inductance and parasitic capacitance of six different pickup coil geometries and compare their sensitivity and usable frequency range. In the pickup coil design, the number of turns and coil section separation are varied from 200 to 400 turns, and 1 to 4 sections, respectively. We find that the usable frequency range is greatly affected by the pickup coil's inductance due to the self-resonance phenomena compared to their parasitic capacitance. A low noise instrument amplifier circuit (AD8429, Analog Devices, USA) was integrated and fabricated on a printed circuit board to amplify the weak signal from the pickup coil. We also implement a generalized Goertzel algorithm to achieve fast signal amplitude and phase extractions at a frequency. The developed magnetometer shows a sensitivity of 10-8 Am2/Hz at 6 Hz and a frequency range of up to 158 kHz. Using the developed AC magnetometer, we demonstrate the viscosity effect on the frequency response of thermally blocked, single-core nanoparticles (SHP30, Ocean Nanotech, USA) in glycerol solutions. The excitation frequency is swept from 5 Hz to 158 kHz at a field amplitude of 0.55 mTpp within the acquisition time of 5 min (51 points). As a result, the viscosity change is confirmed by the peak shifting in the imaginary magnetization curve towards lower frequency values when the wt/V% of the glycerol solution is increased. The hydrodynamic size and the average anisotropy energy ratio σ are estimated to be 60.6 nm and 25, respectively, from the complex AC magnetization. It can be expected that the developed AC magnetometer can be a valuable tool in providing a fast and reliable assessment of MNPs for bio-sensing applications. Institute of Physics 2022-06 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/42682/1/A%20benchtop%20induction-based%20AC%20magnetometer.pdf pdf en http://umpir.ump.edu.my/id/eprint/42682/2/A%20benchtop%20induction-based%20AC%20magnetometer%20for%20a%20fast%20characterization%20of%20magnetic%20nanoparticles_ABS.pdf Mohd Mawardi, Saari and Mohd Herwan, Sulaiman and Hamzah, Ahmad and Nurul Akmal, Che Lah and Sakai, Kenji and Kiwa, Toshihiko and Tsukada, Keiji (2022) A benchtop induction-based AC magnetometer for a fast characterization of magnetic nanoparticles. Engineering Research Express, 4 (025047). pp. 1-9. ISSN 2631-8695. (Published) https://doi.org/10.1088/2631-8695/ac78c8 https://doi.org/10.1088/2631-8695/ac78c8 |
| spellingShingle | T Technology (General) TA Engineering (General). Civil engineering (General) TJ Mechanical engineering and machinery TK Electrical engineering. Electronics Nuclear engineering TS Manufactures Mohd Mawardi, Saari Mohd Herwan, Sulaiman Hamzah, Ahmad Nurul Akmal, Che Lah Sakai, Kenji Kiwa, Toshihiko Tsukada, Keiji A benchtop induction-based AC magnetometer for a fast characterization of magnetic nanoparticles |
| title | A benchtop induction-based AC magnetometer for a fast
characterization of magnetic nanoparticles |
| title_full | A benchtop induction-based AC magnetometer for a fast
characterization of magnetic nanoparticles |
| title_fullStr | A benchtop induction-based AC magnetometer for a fast
characterization of magnetic nanoparticles |
| title_full_unstemmed | A benchtop induction-based AC magnetometer for a fast
characterization of magnetic nanoparticles |
| title_short | A benchtop induction-based AC magnetometer for a fast
characterization of magnetic nanoparticles |
| title_sort | benchtop induction based ac magnetometer for a fast characterization of magnetic nanoparticles |
| topic | T Technology (General) TA Engineering (General). Civil engineering (General) TJ Mechanical engineering and machinery TK Electrical engineering. Electronics Nuclear engineering TS Manufactures |
| url | http://umpir.ump.edu.my/id/eprint/42682/1/A%20benchtop%20induction-based%20AC%20magnetometer.pdf http://umpir.ump.edu.my/id/eprint/42682/2/A%20benchtop%20induction-based%20AC%20magnetometer%20for%20a%20fast%20characterization%20of%20magnetic%20nanoparticles_ABS.pdf |
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