Natural Products R&D Leads from Nature
Natural products have taught researchers about the properties that make molecules adept at getting into cells and binding proteins and the many ways they can fail. However, it moves at a relatively slow pace, entailing the collection and preparation of specimens and the isolation, purification, and...
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Penerbit Universiti Malaysia Pahang
2011
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| Summary: | Natural products have taught researchers about the properties that make molecules adept at getting into cells and binding proteins and the many ways they can fail. However, it moves at a relatively slow pace, entailing the collection and preparation of specimens and the isolation, purification, and structural determination of active agents. Inadvertently these make natural products research appear tedious and expensive. The rapid assays used by pharmaceutical companies demand a steady flow of new compounds to screen. All these factors have led many pharmaceutical companies to cut off natural products programs. |
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