Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues

Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues

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Naturally occurring anthraquinones, damnacanthal (1) and nordamnacanthal (2) were synthesized with modified reaction steps and investigated for their cytotoxicity against the MCF-7 and K-562 cancer cell lines, respectively. Intermediate analogues 2-bromomethyl-1,3-dimethoxyanthraquinone (5, IC50 = 5...

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Bibliographic Details
Main Authors:	Akhtar, Muhammad Nadeem, Seema, Zareen, Swee, Keong Yeap, Wan, Yong Ho, Kong, Mun Lo, Hasan, Aurangzeb, Noorjahan Banu, Alitheen
Format:	Article
Language:	English
Published:	MDPI - Open Access Publishing 2013
Subjects:	QD Chemistry
Online Access:	http://umpir.ump.edu.my/id/eprint/5262/1/FIST%2C_2013._Nadeem.pdf

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