Application of Factorial Design Analysis to Control Bisphenol A MIP fabrication
A key issue in the synthesis of molecular imprinted polymer nanoparticles is the identification and optimization of the main factors affecting the material structure and size. This paper describe an experimental design approach to synthesis bisphenol A molecular imprinted polymer nanoparticles (BPA-...
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2011
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/5830/1/fkksa-2011-KuFaizal-Application_of_factorial_designSOMChe.pdf |
| _version_ | 1796990015037767680 |
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| author | C. K. M., Faizal Shareena, Mohd Sharif |
| author_facet | C. K. M., Faizal Shareena, Mohd Sharif |
| author_sort | C. K. M., Faizal |
| collection | UMP |
| description | A key issue in the synthesis of molecular imprinted polymer nanoparticles is the identification and optimization of the main factors affecting the material structure and size. This paper describe an experimental design approach to synthesis bisphenol A molecular imprinted polymer nanoparticles (BPA-MIP NPs) aimed at analysis of the relationship of four selected parameters: the polymerisation temperature, agitation rate, cross-linker to solvent ratio, and percentage of initiator. The results presented demonstrate the importance of keeping the right balance between these various parameters of polymerisation conditions which are approximately 60oC, 100rpm, 65% solvent ratio and 1% initiator, respectively. Generally, it can be concluded that MIPs should be synthesized using enough heating, adequate agitation, low concentration of initiator and with a bit higher amount of solvent. Such procedure is proven as time and cost effective, and also can be used as a general tool in the preparation of MIP NPs for different target molecules. |
| first_indexed | 2024-03-06T11:45:23Z |
| format | Conference or Workshop Item |
| id | UMPir5830 |
| institution | Universiti Malaysia Pahang |
| language | English |
| last_indexed | 2024-03-06T11:45:23Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | UMPir58302018-01-12T02:59:02Z http://umpir.ump.edu.my/id/eprint/5830/ Application of Factorial Design Analysis to Control Bisphenol A MIP fabrication C. K. M., Faizal Shareena, Mohd Sharif TP Chemical technology A key issue in the synthesis of molecular imprinted polymer nanoparticles is the identification and optimization of the main factors affecting the material structure and size. This paper describe an experimental design approach to synthesis bisphenol A molecular imprinted polymer nanoparticles (BPA-MIP NPs) aimed at analysis of the relationship of four selected parameters: the polymerisation temperature, agitation rate, cross-linker to solvent ratio, and percentage of initiator. The results presented demonstrate the importance of keeping the right balance between these various parameters of polymerisation conditions which are approximately 60oC, 100rpm, 65% solvent ratio and 1% initiator, respectively. Generally, it can be concluded that MIPs should be synthesized using enough heating, adequate agitation, low concentration of initiator and with a bit higher amount of solvent. Such procedure is proven as time and cost effective, and also can be used as a general tool in the preparation of MIP NPs for different target molecules. 2011 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5830/1/fkksa-2011-KuFaizal-Application_of_factorial_designSOMChe.pdf C. K. M., Faizal and Shareena, Mohd Sharif (2011) Application of Factorial Design Analysis to Control Bisphenol A MIP fabrication. In: Proceeding of International Conference Of Chemical Engineering And Industrial Biotechnology In Conjunction With 25th Symposium Of Malaysian Chemical Engineer (ICCEIB-Somche) 2011 , 28 November - 1 December 2011 , Kuantan, Pahang. pp. 1-6.. |
| spellingShingle | TP Chemical technology C. K. M., Faizal Shareena, Mohd Sharif Application of Factorial Design Analysis to Control Bisphenol A MIP fabrication |
| title | Application of Factorial Design Analysis to Control Bisphenol A MIP fabrication |
| title_full | Application of Factorial Design Analysis to Control Bisphenol A MIP fabrication |
| title_fullStr | Application of Factorial Design Analysis to Control Bisphenol A MIP fabrication |
| title_full_unstemmed | Application of Factorial Design Analysis to Control Bisphenol A MIP fabrication |
| title_short | Application of Factorial Design Analysis to Control Bisphenol A MIP fabrication |
| title_sort | application of factorial design analysis to control bisphenol a mip fabrication |
| topic | TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/5830/1/fkksa-2011-KuFaizal-Application_of_factorial_designSOMChe.pdf |
| work_keys_str_mv | AT ckmfaizal applicationoffactorialdesignanalysistocontrolbisphenolamipfabrication AT shareenamohdsharif applicationoffactorialdesignanalysistocontrolbisphenolamipfabrication |