Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis
Molecular imprinted polymer (MIP) has caught the attention of many researches in recent years as a great tool for molecule recognition and other applications. But the main issue in the synthesis of MIP nanoparticles is the identification and optimization of the main factors affecting the material st...
Main Authors: | , |
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Format: | Conference or Workshop Item |
Language: | English |
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2012
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Online Access: | http://umpir.ump.edu.my/id/eprint/5905/1/fkksa-2012-che_ku-Bisphenol_A_MIP.pdf |
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author | C. K. M., Faizal Shareena, Mohd Sharif |
author_facet | C. K. M., Faizal Shareena, Mohd Sharif |
author_sort | C. K. M., Faizal |
collection | UMP |
description | Molecular imprinted polymer (MIP) has caught the attention of many researches in recent years as a great tool for molecule recognition and other applications. But the main issue in the synthesis of MIP nanoparticles is the identification and optimization of the main factors affecting the material structure and size. This paper describe an experimental design approach to synthesis bisphenol A molecular imprinted polymer nanoparticles (BPA-MIP NPs) aimed at analysis of the relationship of four selected parameters: the polymerisation temperature, agitation rate, cross-linker to solvent ratio, and percentage of initiator. The results presented demonstrate the importance of keeping the right balance between these various parameters of polymerisation conditions. Generally, it can be concluded that MIPs should be synthesized using enough heating, adequate agitation, low concentration of initiator and with a considerably higher amount of solvent. Such procedure is proven as time and cost effective, and also can be used as a general tool in the preparation of MIPs for many different target molecules. |
first_indexed | 2024-03-06T11:45:30Z |
format | Conference or Workshop Item |
id | UMPir5905 |
institution | Universiti Malaysia Pahang |
language | English |
last_indexed | 2024-03-06T11:45:30Z |
publishDate | 2012 |
record_format | dspace |
spelling | UMPir59052018-01-12T02:43:06Z http://umpir.ump.edu.my/id/eprint/5905/ Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis C. K. M., Faizal Shareena, Mohd Sharif TP Chemical technology Molecular imprinted polymer (MIP) has caught the attention of many researches in recent years as a great tool for molecule recognition and other applications. But the main issue in the synthesis of MIP nanoparticles is the identification and optimization of the main factors affecting the material structure and size. This paper describe an experimental design approach to synthesis bisphenol A molecular imprinted polymer nanoparticles (BPA-MIP NPs) aimed at analysis of the relationship of four selected parameters: the polymerisation temperature, agitation rate, cross-linker to solvent ratio, and percentage of initiator. The results presented demonstrate the importance of keeping the right balance between these various parameters of polymerisation conditions. Generally, it can be concluded that MIPs should be synthesized using enough heating, adequate agitation, low concentration of initiator and with a considerably higher amount of solvent. Such procedure is proven as time and cost effective, and also can be used as a general tool in the preparation of MIPs for many different target molecules. 2012 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5905/1/fkksa-2012-che_ku-Bisphenol_A_MIP.pdf C. K. M., Faizal and Shareena, Mohd Sharif (2012) Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis. In: International Conference on Nanotechnology 2012 , 30 May-1 June 2012 , Kuala Lumpur. pp. 1-12.. |
spellingShingle | TP Chemical technology C. K. M., Faizal Shareena, Mohd Sharif Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis |
title | Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis |
title_full | Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis |
title_fullStr | Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis |
title_full_unstemmed | Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis |
title_short | Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis |
title_sort | bisphenol a mip fabrication using the application of factorial design analysis |
topic | TP Chemical technology |
url | http://umpir.ump.edu.my/id/eprint/5905/1/fkksa-2012-che_ku-Bisphenol_A_MIP.pdf |
work_keys_str_mv | AT ckmfaizal bisphenolamipfabricationusingtheapplicationoffactorialdesignanalysis AT shareenamohdsharif bisphenolamipfabricationusingtheapplicationoffactorialdesignanalysis |