Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis

Molecular imprinted polymer (MIP) has caught the attention of many researches in recent years as a great tool for molecule recognition and other applications. But the main issue in the synthesis of MIP nanoparticles is the identification and optimization of the main factors affecting the material st...

Full description

Bibliographic Details
Main Authors: C. K. M., Faizal, Shareena, Mohd Sharif
Format: Conference or Workshop Item
Language:English
Published: 2012
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/5905/1/fkksa-2012-che_ku-Bisphenol_A_MIP.pdf
_version_ 1796990022134530048
author C. K. M., Faizal
Shareena, Mohd Sharif
author_facet C. K. M., Faizal
Shareena, Mohd Sharif
author_sort C. K. M., Faizal
collection UMP
description Molecular imprinted polymer (MIP) has caught the attention of many researches in recent years as a great tool for molecule recognition and other applications. But the main issue in the synthesis of MIP nanoparticles is the identification and optimization of the main factors affecting the material structure and size. This paper describe an experimental design approach to synthesis bisphenol A molecular imprinted polymer nanoparticles (BPA-MIP NPs) aimed at analysis of the relationship of four selected parameters: the polymerisation temperature, agitation rate, cross-linker to solvent ratio, and percentage of initiator. The results presented demonstrate the importance of keeping the right balance between these various parameters of polymerisation conditions. Generally, it can be concluded that MIPs should be synthesized using enough heating, adequate agitation, low concentration of initiator and with a considerably higher amount of solvent. Such procedure is proven as time and cost effective, and also can be used as a general tool in the preparation of MIPs for many different target molecules.
first_indexed 2024-03-06T11:45:30Z
format Conference or Workshop Item
id UMPir5905
institution Universiti Malaysia Pahang
language English
last_indexed 2024-03-06T11:45:30Z
publishDate 2012
record_format dspace
spelling UMPir59052018-01-12T02:43:06Z http://umpir.ump.edu.my/id/eprint/5905/ Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis C. K. M., Faizal Shareena, Mohd Sharif TP Chemical technology Molecular imprinted polymer (MIP) has caught the attention of many researches in recent years as a great tool for molecule recognition and other applications. But the main issue in the synthesis of MIP nanoparticles is the identification and optimization of the main factors affecting the material structure and size. This paper describe an experimental design approach to synthesis bisphenol A molecular imprinted polymer nanoparticles (BPA-MIP NPs) aimed at analysis of the relationship of four selected parameters: the polymerisation temperature, agitation rate, cross-linker to solvent ratio, and percentage of initiator. The results presented demonstrate the importance of keeping the right balance between these various parameters of polymerisation conditions. Generally, it can be concluded that MIPs should be synthesized using enough heating, adequate agitation, low concentration of initiator and with a considerably higher amount of solvent. Such procedure is proven as time and cost effective, and also can be used as a general tool in the preparation of MIPs for many different target molecules. 2012 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5905/1/fkksa-2012-che_ku-Bisphenol_A_MIP.pdf C. K. M., Faizal and Shareena, Mohd Sharif (2012) Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis. In: International Conference on Nanotechnology 2012 , 30 May-1 June 2012 , Kuala Lumpur. pp. 1-12..
spellingShingle TP Chemical technology
C. K. M., Faizal
Shareena, Mohd Sharif
Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis
title Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis
title_full Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis
title_fullStr Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis
title_full_unstemmed Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis
title_short Bisphenol A MIP Fabrication using the Application of Factorial Design Analysis
title_sort bisphenol a mip fabrication using the application of factorial design analysis
topic TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/5905/1/fkksa-2012-che_ku-Bisphenol_A_MIP.pdf
work_keys_str_mv AT ckmfaizal bisphenolamipfabricationusingtheapplicationoffactorialdesignanalysis
AT shareenamohdsharif bisphenolamipfabricationusingtheapplicationoffactorialdesignanalysis