Monovalent Maleimide Functionalization of Gold Nanoparticles Via Copper-Free Click Chemistry
A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.
Bibliographic Details
Main Authors: |
D. J., Nieves,
N. S., Azmi,
R., Xu,
R., Levy,
E. A., Yates,
D. G., Fernig |
Format: | Article
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Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | http://umpir.ump.edu.my/id/eprint/7877/1/Monovalent_maleimide_functionalization_of_gold_nanoparticles_via_copper-free_click_chemistry.pdf
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