Monovalent Maleimide Functionalization of Gold Nanoparticles Via Copper-Free Click Chemistry

A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.

Bibliographic Details
Main Authors: D. J., Nieves, N. S., Azmi, R., Xu, R., Levy, E. A., Yates, D. G., Fernig
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/7877/1/Monovalent_maleimide_functionalization_of_gold_nanoparticles_via_copper-free_click_chemistry.pdf
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author D. J., Nieves
N. S., Azmi
R., Xu
R., Levy
E. A., Yates
D. G., Fernig
author_facet D. J., Nieves
N. S., Azmi
R., Xu
R., Levy
E. A., Yates
D. G., Fernig
author_sort D. J., Nieves
collection UMP
description A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.
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spelling UMPir78772016-04-25T01:11:12Z http://umpir.ump.edu.my/id/eprint/7877/ Monovalent Maleimide Functionalization of Gold Nanoparticles Via Copper-Free Click Chemistry D. J., Nieves N. S., Azmi R., Xu R., Levy E. A., Yates D. G., Fernig Q Science (General) A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition. 2014 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/7877/1/Monovalent_maleimide_functionalization_of_gold_nanoparticles_via_copper-free_click_chemistry.pdf D. J., Nieves and N. S., Azmi and R., Xu and R., Levy and E. A., Yates and D. G., Fernig (2014) Monovalent Maleimide Functionalization of Gold Nanoparticles Via Copper-Free Click Chemistry. Communication, 50. pp. 13157-13160. (Published) http://dx.doi.org/10.1039/c4cc05909c DOI: 10.1039/c4cc05909c
spellingShingle Q Science (General)
D. J., Nieves
N. S., Azmi
R., Xu
R., Levy
E. A., Yates
D. G., Fernig
Monovalent Maleimide Functionalization of Gold Nanoparticles Via Copper-Free Click Chemistry
title Monovalent Maleimide Functionalization of Gold Nanoparticles Via Copper-Free Click Chemistry
title_full Monovalent Maleimide Functionalization of Gold Nanoparticles Via Copper-Free Click Chemistry
title_fullStr Monovalent Maleimide Functionalization of Gold Nanoparticles Via Copper-Free Click Chemistry
title_full_unstemmed Monovalent Maleimide Functionalization of Gold Nanoparticles Via Copper-Free Click Chemistry
title_short Monovalent Maleimide Functionalization of Gold Nanoparticles Via Copper-Free Click Chemistry
title_sort monovalent maleimide functionalization of gold nanoparticles via copper free click chemistry
topic Q Science (General)
url http://umpir.ump.edu.my/id/eprint/7877/1/Monovalent_maleimide_functionalization_of_gold_nanoparticles_via_copper-free_click_chemistry.pdf
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