Biomimetic Growth of Bone-Like Apatite Via Simulated Body Fluid on Hydroxyethyl Cellulose/Polyvinyl Alcohol Electrospun Nanofibers

In this study, randomly oriented hydroxyethyl cellulose/polyvinyl alcohol (HEC/PVA) nanofibers were fabricated by electrospinning. The blend solutions of HEC/PVA with different weight ratio of HEC to PVA were prepared using water as solvent to fabricate nanofibers. These nanofibrous scaffolds were c...

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Main Authors: Sugandha, Chahal, Jahir Hussain, Fathima Shahitha, M. M., Yusoff
Format: Article
Language:English
Published: IOS Press 2014
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/8208/1/fist-2014-chalal-Biomimetic%20Growth%20of%20Bone-Like%20Apatite%20Via%20Simulated%20.pdf
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author Sugandha, Chahal
Jahir Hussain, Fathima Shahitha
M. M., Yusoff
author_facet Sugandha, Chahal
Jahir Hussain, Fathima Shahitha
M. M., Yusoff
author_sort Sugandha, Chahal
collection UMP
description In this study, randomly oriented hydroxyethyl cellulose/polyvinyl alcohol (HEC/PVA) nanofibers were fabricated by electrospinning. The blend solutions of HEC/PVA with different weight ratio of HEC to PVA were prepared using water as solvent to fabricate nanofibers. These nanofibrous scaffolds were coated with bone-like apatite by immersing into 10x simulated body fluid (SBF) for different time periods. The morphology and structure of the nanofibers were characterized by SEM, FTIR and DSC. FESEM-EDS and FTIR analysis were used to confirm the deposition of apatite on the surface of nanofibers. The results of this study suggest that this apatite coated nanofibrous scaffolds could be a suitable biomaterial for bone tissue engineering.
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spelling UMPir82082018-07-27T08:28:05Z http://umpir.ump.edu.my/id/eprint/8208/ Biomimetic Growth of Bone-Like Apatite Via Simulated Body Fluid on Hydroxyethyl Cellulose/Polyvinyl Alcohol Electrospun Nanofibers Sugandha, Chahal Jahir Hussain, Fathima Shahitha M. M., Yusoff QD Chemistry In this study, randomly oriented hydroxyethyl cellulose/polyvinyl alcohol (HEC/PVA) nanofibers were fabricated by electrospinning. The blend solutions of HEC/PVA with different weight ratio of HEC to PVA were prepared using water as solvent to fabricate nanofibers. These nanofibrous scaffolds were coated with bone-like apatite by immersing into 10x simulated body fluid (SBF) for different time periods. The morphology and structure of the nanofibers were characterized by SEM, FTIR and DSC. FESEM-EDS and FTIR analysis were used to confirm the deposition of apatite on the surface of nanofibers. The results of this study suggest that this apatite coated nanofibrous scaffolds could be a suitable biomaterial for bone tissue engineering. IOS Press 2014 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/8208/1/fist-2014-chalal-Biomimetic%20Growth%20of%20Bone-Like%20Apatite%20Via%20Simulated%20.pdf Sugandha, Chahal and Jahir Hussain, Fathima Shahitha and M. M., Yusoff (2014) Biomimetic Growth of Bone-Like Apatite Via Simulated Body Fluid on Hydroxyethyl Cellulose/Polyvinyl Alcohol Electrospun Nanofibers. Bio-Medical Materials and Engineering, 24 (1). pp. 799-806. ISSN 0959-2989 (Print); 1878-3619 (Online). (Published) http://dx.doi.org/10.3233/BME-130871 DOI 10.3233/BME-130871
spellingShingle QD Chemistry
Sugandha, Chahal
Jahir Hussain, Fathima Shahitha
M. M., Yusoff
Biomimetic Growth of Bone-Like Apatite Via Simulated Body Fluid on Hydroxyethyl Cellulose/Polyvinyl Alcohol Electrospun Nanofibers
title Biomimetic Growth of Bone-Like Apatite Via Simulated Body Fluid on Hydroxyethyl Cellulose/Polyvinyl Alcohol Electrospun Nanofibers
title_full Biomimetic Growth of Bone-Like Apatite Via Simulated Body Fluid on Hydroxyethyl Cellulose/Polyvinyl Alcohol Electrospun Nanofibers
title_fullStr Biomimetic Growth of Bone-Like Apatite Via Simulated Body Fluid on Hydroxyethyl Cellulose/Polyvinyl Alcohol Electrospun Nanofibers
title_full_unstemmed Biomimetic Growth of Bone-Like Apatite Via Simulated Body Fluid on Hydroxyethyl Cellulose/Polyvinyl Alcohol Electrospun Nanofibers
title_short Biomimetic Growth of Bone-Like Apatite Via Simulated Body Fluid on Hydroxyethyl Cellulose/Polyvinyl Alcohol Electrospun Nanofibers
title_sort biomimetic growth of bone like apatite via simulated body fluid on hydroxyethyl cellulose polyvinyl alcohol electrospun nanofibers
topic QD Chemistry
url http://umpir.ump.edu.my/id/eprint/8208/1/fist-2014-chalal-Biomimetic%20Growth%20of%20Bone-Like%20Apatite%20Via%20Simulated%20.pdf
work_keys_str_mv AT sugandhachahal biomimeticgrowthofbonelikeapatiteviasimulatedbodyfluidonhydroxyethylcellulosepolyvinylalcoholelectrospunnanofibers
AT jahirhussainfathimashahitha biomimeticgrowthofbonelikeapatiteviasimulatedbodyfluidonhydroxyethylcellulosepolyvinylalcoholelectrospunnanofibers
AT mmyusoff biomimeticgrowthofbonelikeapatiteviasimulatedbodyfluidonhydroxyethylcellulosepolyvinylalcoholelectrospunnanofibers