In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract
Introduction: Currently, researchers are aiming to explore herbal plants to replace synthetic drugs because herbal plants contain high active compounds and fewer side effects. Our study was done to determine the antibacterial activity of Eurycoma longifolia Jack (E. longifolia) root using ethanol ba...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
2015
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/9418/1/In%20Vitro%20Antibacterial%20Activity%20of%20Eurycoma%20Longifolia%20Jack%20%28Tongkat%20Ali%29%20Root%20Extract.pdf |
| _version_ | 1825822275296821248 |
|---|---|
| author | Najmuldeen, Ghazi Faisal G. G., Faisal S. M., Zakaria |
| author_facet | Najmuldeen, Ghazi Faisal G. G., Faisal S. M., Zakaria |
| author_sort | Najmuldeen, Ghazi Faisal |
| collection | UMP |
| description | Introduction: Currently, researchers are aiming to explore herbal plants to replace synthetic drugs because herbal plants contain high active compounds and fewer side effects. Our study was done to determine the antibacterial activity of Eurycoma longifolia Jack (E. longifolia) root using ethanol based extract. Methods: Five types of pathogenic bacterial strains were used; Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative (Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa). Disc diffusion assay and Minimum Inhibitory Concentration (MIC) tests were used to determine the inhibition zone and turbidity of suspension which reflects the antibacterial activity of the extract. Results: The ethanolic extract of E. longifolia Jack root extract showed positive results against Gram-positive bacteria (S. aureus and B. cereus) and Gramnegative (S. typhi). B.cereus and S.typhi showed inhibition zone values of 11.76mm and 14.33mm at the extract concentration of 150mg/ml that were higher than the positive control values (9.00, 12.67mm) respectively. However, E. coli and P. aeruginosa did not show any inhibition by the ethanol-based extract. Conclusion: From the results we can conclude that E.Longifolia root extract possesses antibacterial activity that can be further explored to produce new medicinal products. |
| first_indexed | 2024-03-06T11:54:09Z |
| format | Article |
| id | UMPir9418 |
| institution | Universiti Malaysia Pahang |
| language | English |
| last_indexed | 2024-03-06T11:54:09Z |
| publishDate | 2015 |
| record_format | dspace |
| spelling | UMPir94182016-04-13T02:00:22Z http://umpir.ump.edu.my/id/eprint/9418/ In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract Najmuldeen, Ghazi Faisal G. G., Faisal S. M., Zakaria TP Chemical technology Introduction: Currently, researchers are aiming to explore herbal plants to replace synthetic drugs because herbal plants contain high active compounds and fewer side effects. Our study was done to determine the antibacterial activity of Eurycoma longifolia Jack (E. longifolia) root using ethanol based extract. Methods: Five types of pathogenic bacterial strains were used; Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative (Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa). Disc diffusion assay and Minimum Inhibitory Concentration (MIC) tests were used to determine the inhibition zone and turbidity of suspension which reflects the antibacterial activity of the extract. Results: The ethanolic extract of E. longifolia Jack root extract showed positive results against Gram-positive bacteria (S. aureus and B. cereus) and Gramnegative (S. typhi). B.cereus and S.typhi showed inhibition zone values of 11.76mm and 14.33mm at the extract concentration of 150mg/ml that were higher than the positive control values (9.00, 12.67mm) respectively. However, E. coli and P. aeruginosa did not show any inhibition by the ethanol-based extract. Conclusion: From the results we can conclude that E.Longifolia root extract possesses antibacterial activity that can be further explored to produce new medicinal products. 2015 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/9418/1/In%20Vitro%20Antibacterial%20Activity%20of%20Eurycoma%20Longifolia%20Jack%20%28Tongkat%20Ali%29%20Root%20Extract.pdf Najmuldeen, Ghazi Faisal and G. G., Faisal and S. M., Zakaria (2015) In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract. The International Medical Journal Malaysia, 14 (1). pp. 77-81. (Published) http://journals.iium.edu.my/imjm/index.php/eimj/article/view/225 |
| spellingShingle | TP Chemical technology Najmuldeen, Ghazi Faisal G. G., Faisal S. M., Zakaria In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract |
| title | In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract |
| title_full | In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract |
| title_fullStr | In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract |
| title_full_unstemmed | In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract |
| title_short | In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract |
| title_sort | in vitro antibacterial activity of eurycoma longifolia jack tongkat ali root extract |
| topic | TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/9418/1/In%20Vitro%20Antibacterial%20Activity%20of%20Eurycoma%20Longifolia%20Jack%20%28Tongkat%20Ali%29%20Root%20Extract.pdf |
| work_keys_str_mv | AT najmuldeenghazifaisal invitroantibacterialactivityofeurycomalongifoliajacktongkatalirootextract AT ggfaisal invitroantibacterialactivityofeurycomalongifoliajacktongkatalirootextract AT smzakaria invitroantibacterialactivityofeurycomalongifoliajacktongkatalirootextract |