Ospemifene for vulvar and vaginal atrophy: an overview
The menopause-related decline in estrogen levels leads to an array of genital, sexual, and urinary symptoms collectively known as genitourinary syndrome of menopause. The constellation of symptoms associated with vulvar and vaginal atrophy (VVA) can have a profoundly detrimental effect on a woman’s...
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| Format: | Article |
| Language: | English |
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BioExcel Publishing Ltd
2020-07-01
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| Series: | Drugs in Context |
| Subjects: | |
| Online Access: | https://www.drugsincontext.com/ospemifene-for-vulvar-and-vaginal-atrophy:-an-overview/ |
| _version_ | 1818289780122714112 |
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| author | Santiago Palacios |
| author_facet | Santiago Palacios |
| author_sort | Santiago Palacios |
| collection | DOAJ |
| description | The menopause-related decline in estrogen levels leads to an array of genital, sexual, and urinary symptoms collectively known as genitourinary syndrome of menopause. The constellation of symptoms associated with vulvar and vaginal atrophy (VVA) can have a profoundly detrimental effect on a woman’s sexual function, relationships, and quality of life. Ospemifene is a selective estrogen receptor modulator indicated for treatment of moderate-to-severe symptomatic VVA in postmenopausal women who are not candidates for local vaginal estrogen therapy or have contraindications for estrogen products. Ospemifene is administered orally, thus avoiding the inconveniences of local therapy, and can be used in women with VVA and a history of breast cancer after completing all (including adjuvant) breast cancer treatment. As well as restoring vaginal health in symptomatic VVA, ospemifene may have collateral benefits of importance to postmenopausal women. In this Special Issue entitled “Treatment of Vulvar and Vaginal Atrophy: Clinical Experience with Ospemifene,” illustrative case studies examine the experiences of women with VVA during treatment with ospemifene. Specific topics include the effects of ospemifene on bone markers; its use in breast cancer survivors and in women with dyslipidemia, urinary incontinence, or VVA-related sexual dysfunction; and its concomitant use with laser therapy. |
| first_indexed | 2024-12-13T02:17:43Z |
| format | Article |
| id | doaj.art-0001c8ae35bb4c7b9e3e4d64a3d473d2 |
| institution | Directory Open Access Journal |
| issn | 1740-4398 1740-4398 |
| language | English |
| last_indexed | 2024-12-13T02:17:43Z |
| publishDate | 2020-07-01 |
| publisher | BioExcel Publishing Ltd |
| record_format | Article |
| series | Drugs in Context |
| spelling | doaj.art-0001c8ae35bb4c7b9e3e4d64a3d473d22022-12-22T00:02:51ZengBioExcel Publishing LtdDrugs in Context1740-43981740-43982020-07-0191510.7573/dic.2020-3-2Ospemifene for vulvar and vaginal atrophy: an overviewSantiago PalaciosThe menopause-related decline in estrogen levels leads to an array of genital, sexual, and urinary symptoms collectively known as genitourinary syndrome of menopause. The constellation of symptoms associated with vulvar and vaginal atrophy (VVA) can have a profoundly detrimental effect on a woman’s sexual function, relationships, and quality of life. Ospemifene is a selective estrogen receptor modulator indicated for treatment of moderate-to-severe symptomatic VVA in postmenopausal women who are not candidates for local vaginal estrogen therapy or have contraindications for estrogen products. Ospemifene is administered orally, thus avoiding the inconveniences of local therapy, and can be used in women with VVA and a history of breast cancer after completing all (including adjuvant) breast cancer treatment. As well as restoring vaginal health in symptomatic VVA, ospemifene may have collateral benefits of importance to postmenopausal women. In this Special Issue entitled “Treatment of Vulvar and Vaginal Atrophy: Clinical Experience with Ospemifene,” illustrative case studies examine the experiences of women with VVA during treatment with ospemifene. Specific topics include the effects of ospemifene on bone markers; its use in breast cancer survivors and in women with dyslipidemia, urinary incontinence, or VVA-related sexual dysfunction; and its concomitant use with laser therapy.https://www.drugsincontext.com/ospemifene-for-vulvar-and-vaginal-atrophy:-an-overview/genitourinary syndrome of menopauseospemifeneselective estrogen receptor modulatorsvulvar and vaginal atrophy |
| spellingShingle | Santiago Palacios Ospemifene for vulvar and vaginal atrophy: an overview Drugs in Context genitourinary syndrome of menopause ospemifene selective estrogen receptor modulators vulvar and vaginal atrophy |
| title | Ospemifene for vulvar and vaginal atrophy: an overview |
| title_full | Ospemifene for vulvar and vaginal atrophy: an overview |
| title_fullStr | Ospemifene for vulvar and vaginal atrophy: an overview |
| title_full_unstemmed | Ospemifene for vulvar and vaginal atrophy: an overview |
| title_short | Ospemifene for vulvar and vaginal atrophy: an overview |
| title_sort | ospemifene for vulvar and vaginal atrophy an overview |
| topic | genitourinary syndrome of menopause ospemifene selective estrogen receptor modulators vulvar and vaginal atrophy |
| url | https://www.drugsincontext.com/ospemifene-for-vulvar-and-vaginal-atrophy:-an-overview/ |
| work_keys_str_mv | AT santiagopalacios ospemifeneforvulvarandvaginalatrophyanoverview |