Prolactin receptor signaling induces acquisition of chemoresistance and reduces clonogenicity in acute myeloid leukemia

Prolactin receptor signaling induces acquisition of chemoresistance and reduces clonogenicity in acute myeloid leukemia

Abstract Background Development of precision medicine requires the identification of easily detectable and druggable biomarkers. Despite recent targeted drug approvals, prognosis of acute myeloid leukemia (AML) patients needs to be greatly improved, as relapse and refractory disease are still diffic...

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Bibliographic Details
Main Authors: Laia Cuesta-Casanovas, Jennifer Delgado-Martínez, Josep M. Cornet-Masana, José M. Carbó, Antònia Banús-Mulet, Francesca Guijarro, Jordi Esteve, Ruth M. Risueño
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Cancer Cell International
Subjects:
Prolactin receptor
Leukemia
Senescence
Biomarker
Differentiation
Online Access:https://doi.org/10.1186/s12935-023-02944-4

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