A New Strategy for Efficient Screening and Identification of Monoclonal Antibodies against Oncogenic Avian Herpesvirus Utilizing CRISPR/Cas9-Based Gene-Editing Technology
Marek’s disease virus (MDV) is an important oncogenic α-herpesvirus that induces Marek’s disease (MD), characterized by severe immunosuppression and rapid-onset T-cell lymphomas in its natural chicken hosts. Historically, MD is regarded as an ideal biomedical model for studying virally induced cance...
Main Authors: | Man Teng, Zi-Yu Zhou, Yongxiu Yao, Venugopal Nair, Gai-Ping Zhang, Jun Luo |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-09-01
|
Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/14/9/2045 |
Similar Items
-
Efficient Cross-Screening and Characterization of Monoclonal Antibodies against Marek’s Disease Specific Meq Oncoprotein Using CRISPR/Cas9-Gene-Edited Viruses
by: Man Teng, et al.
Published: (2023-03-01) -
V5 and GFP Tagging of Viral Gene pp38 of Marek’s Disease Vaccine Strain CVI988 Using CRISPR/Cas9 Editing
by: Weicheng Li, et al.
Published: (2022-02-01) -
Targeted Editing of the <i>pp38</i> Gene in Marek’s Disease Virus-Transformed Cell Lines Using CRISPR/Cas9 System
by: Yaoyao Zhang, et al.
Published: (2019-04-01) -
Application of CRISPR/Cas9 Gene Editing System on MDV-1 Genome for the Study of Gene Function
by: Yaoyao Zhang, et al.
Published: (2018-05-01) -
Application of CRISPR/Cas9 for Rapid Genome Editing of Pseudorabies Virus and Bovine Herpesvirus-1
by: Wanqi Yu, et al.
Published: (2024-02-01)