A case of psoriasiform graft-versus-host disease

A rare case of psoriasiform graft-versus-host disease is reported. The patient suffered from acute B-cell leukemia for more than 1 year. Nine months after allogenic hematopoietic stem cell transplantation, the patient developed red papules and plaques, with Auspitz sign positive and silver-white sca...

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Bibliographic Details
Main Authors: Jinping HUANG, Ju WEN, Ting LI, Si QIN, Yuchan ZHOU, Rongchang ZHENG
Format: Article
Language:zho
Published: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology 2022-06-01
Series:Pifu-xingbing zhenliaoxue zazhi
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Online Access:http://pfxbzlx.gdvdc.com/CN/10.3969/j.issn.1674-8468.2022.03.012
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Summary:A rare case of psoriasiform graft-versus-host disease is reported. The patient suffered from acute B-cell leukemia for more than 1 year. Nine months after allogenic hematopoietic stem cell transplantation, the patient developed red papules and plaques, with Auspitz sign positive and silver-white scales on the head, face, limb and trunk. The histopathology showed both psoriatic and interfacial dermatitis. Immunohistochemical staining demonstrated infiltration of CD4+ and CD8+ T cells. Diagnosis was psoriasiform graft-versus-host disease. Lesions were improved by topical 0.1% tacrolimus ointment.
ISSN:1674-8468