NOTCH Signaling in Mantle Cell Lymphoma: Biological and Clinical Implications

NOTCH Signaling in Mantle Cell Lymphoma: Biological and Clinical Implications

Despite major progress in mantle cell lymphoma (MCL) therapeutics, MCL remains a deadly disease with a median survival not exceeding four years. No single driver genetic lesion has been described to solely give rise to MCL. The hallmark translocation t(11;14)(q13;q32) requires additional genetic alt...

Full description

Bibliographic Details
Main Authors: Leigh Deshotels, Firas M. Safa, Nakhle S. Saba
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
mantle cell lymphoma
MCL
NOTCH1
NOTCH2
MYC
Online Access:https://www.mdpi.com/1422-0067/24/12/10280

Similar Items

Similar Items