Construction and Manipulation of Serial Gradient Dilution Array on a Microfluidic Slipchip for Screening and Characterizing Inhibitors against Human Pancreatic Lipase

Construction and Manipulation of Serial Gradient Dilution Array on a Microfluidic Slipchip for Screening and Characterizing Inhibitors against Human Pancreatic Lipase

Obesity is one of the foremost public health concerns. Human pancreatic lipase (hPL), a crucial digestive enzyme responsible for the digestion of dietary lipids in humans, has been validated as an important therapeutic target for preventing and treating obesity. The serial dilution technique is comm...

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Bibliographic Details
Main Authors: Junqiang Yang, Yanyan Deng, Min Zhang, Shilun Feng, Sheng Peng, Shijia Yang, Peirong Liu, Gaozhe Cai, Guangbo Ge
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biosensors
Subjects:
microfluidic
SlipChip
serial gradient dilution
obesity
human pancreatic lipase
inhibitors
Online Access:https://www.mdpi.com/2079-6374/13/2/274

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