Role of Goats in the Epidemiology of <i>Coxiella burnetii</i>
Since its first description in the late 1930s, Q fever has raised many questions. <i>Coxiella burnetii</i>, the causative agent, is a zoonotic pathogen affecting a wide range of hosts. This airborne organism leads to an obligate, intracellular lifecycle, during which it multiplies in the...
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| Format: | Article |
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MDPI AG
2022-11-01
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| Series: | Biology |
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| Online Access: | https://www.mdpi.com/2079-7737/11/12/1703 |
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| author | Sofia Anastácio Sérgio Ramalho de Sousa Maria José Saavedra Gabriela Jorge da Silva |
| author_facet | Sofia Anastácio Sérgio Ramalho de Sousa Maria José Saavedra Gabriela Jorge da Silva |
| author_sort | Sofia Anastácio |
| collection | DOAJ |
| description | Since its first description in the late 1930s, Q fever has raised many questions. <i>Coxiella burnetii</i>, the causative agent, is a zoonotic pathogen affecting a wide range of hosts. This airborne organism leads to an obligate, intracellular lifecycle, during which it multiplies in the mononuclear cells of the immune system and in the trophoblasts of the placenta in pregnant females. Although some issues about <i>C. burnetii</i> and its pathogenesis in animals remain unclear, over the years, some experimental studies on Q fever have been conducted in goats given their excretion pattern. Goats play an important role in the epidemiology and economics of <i>C. burnetii</i> infections, also being the focus of several epidemiological studies. Additionally, variants of the agent implicated in human long-term disease have been found circulating in goats. The purpose of this review is to summarize the latest research on <i>C. burnetii</i> infection and the role played by goats in the transmission of the infection to humans. |
| first_indexed | 2024-03-09T17:18:47Z |
| format | Article |
| id | doaj.art-000d87494c1242abb34165004460bdce |
| institution | Directory Open Access Journal |
| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-09T17:18:47Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj.art-000d87494c1242abb34165004460bdce2023-11-24T13:21:55ZengMDPI AGBiology2079-77372022-11-011112170310.3390/biology11121703Role of Goats in the Epidemiology of <i>Coxiella burnetii</i>Sofia Anastácio0Sérgio Ramalho de Sousa1Maria José Saavedra2Gabriela Jorge da Silva3Vasco da Gama Research Centre (CIVG), Department of Veterinary Sciences, Vasco da Gama University School, Avenida José R. Sousa Fernandes 197 Lordemão, 3020-210 Coimbra, PortugalVasco da Gama Research Centre (CIVG), Department of Veterinary Sciences, Vasco da Gama University School, Avenida José R. Sousa Fernandes 197 Lordemão, 3020-210 Coimbra, PortugalLaboratory Medical Microbiology—Antimicrobials, Biocides and Biofilms Unit, Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Trás-os-Montes e Alto Douro, Quinta de Prados, 5000-801 Vila Real, PortugalCenter of Neurosciences and Cell Biology, Health Science Campus, 3000-548 Coimbra, PortugalSince its first description in the late 1930s, Q fever has raised many questions. <i>Coxiella burnetii</i>, the causative agent, is a zoonotic pathogen affecting a wide range of hosts. This airborne organism leads to an obligate, intracellular lifecycle, during which it multiplies in the mononuclear cells of the immune system and in the trophoblasts of the placenta in pregnant females. Although some issues about <i>C. burnetii</i> and its pathogenesis in animals remain unclear, over the years, some experimental studies on Q fever have been conducted in goats given their excretion pattern. Goats play an important role in the epidemiology and economics of <i>C. burnetii</i> infections, also being the focus of several epidemiological studies. Additionally, variants of the agent implicated in human long-term disease have been found circulating in goats. The purpose of this review is to summarize the latest research on <i>C. burnetii</i> infection and the role played by goats in the transmission of the infection to humans.https://www.mdpi.com/2079-7737/11/12/1703zoonosis<i>C. burnetii</i>prevalenceoutbreaksgenotype |
| spellingShingle | Sofia Anastácio Sérgio Ramalho de Sousa Maria José Saavedra Gabriela Jorge da Silva Role of Goats in the Epidemiology of <i>Coxiella burnetii</i> Biology zoonosis <i>C. burnetii</i> prevalence outbreaks genotype |
| title | Role of Goats in the Epidemiology of <i>Coxiella burnetii</i> |
| title_full | Role of Goats in the Epidemiology of <i>Coxiella burnetii</i> |
| title_fullStr | Role of Goats in the Epidemiology of <i>Coxiella burnetii</i> |
| title_full_unstemmed | Role of Goats in the Epidemiology of <i>Coxiella burnetii</i> |
| title_short | Role of Goats in the Epidemiology of <i>Coxiella burnetii</i> |
| title_sort | role of goats in the epidemiology of i coxiella burnetii i |
| topic | zoonosis <i>C. burnetii</i> prevalence outbreaks genotype |
| url | https://www.mdpi.com/2079-7737/11/12/1703 |
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