Targeting Glutaminase by Natural Compounds: Structure-Based Virtual Screening and Molecular Dynamics Simulation Approach to Suppress Cancer Progression

Targeting Glutaminase by Natural Compounds: Structure-Based Virtual Screening and Molecular Dynamics Simulation Approach to Suppress Cancer Progression

Cancer cells change their glucose and glutamine (GLU) metabolism to obtain the energy required to continue growing. Glutaminase (GLS) plays a crucial role in promoting cell metabolism for cancer cell growth; targeting GLU metabolism by inhibiting GLS has attracted interest as a potential cancer mana...

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Bibliographic Details
Main Authors:	Shams Tabrez, Torki A. Zughaibi, Mehboob Hoque, Mohd Suhail, Mohammad Imran Khan, Azhar U. Khan
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Series:	Molecules
Subjects:	glutamine cancer glutaminase natural compounds
Online Access:	https://www.mdpi.com/1420-3049/27/15/5042

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