Optimized production, purification, and radiolabeling of the 203Pb/212Pb theranostic pair for nuclear medicine

Optimized production, purification, and radiolabeling of the 203Pb/212Pb theranostic pair for nuclear medicine

Abstract TRIUMF is one of the only laboratories in the world able to produce both lead-203 (203Pb, t1/2 = 51.9 h) and 212Pb (t1/2 = 10.6 h) onsite via its 13 and 500 MeV cyclotrons, respectively. Together, 203Pb and 212Pb form an element-equivalent theranostic pair that potentiate image-guided, pers...

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Bibliographic Details
Main Authors: Brooke L. McNeil, Simona A. Mastroianni, Scott W. McNeil, Stefan Zeisler, Joel Kumlin, Sogol Borjian, Anthony W. McDonagh, Michael Cross, Paul Schaffer, Caterina F. Ramogida
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37313-8

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