Structural Design, Synthesis and Antioxidant, Antileishmania, Anti-Inflammatory and Anticancer Activities of a Novel Quercetin Acetylated Derivative

Structural Design, Synthesis and Antioxidant, Antileishmania, Anti-Inflammatory and Anticancer Activities of a Novel Quercetin Acetylated Derivative

Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural modification in Q by acetylation, thus, obtaining the quercetin...

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Bibliographic Details
Main Authors: Saul Vislei Simões da Silva, Orlando Maia Barboza, Jéssica Teles Souza, Érica Novaes Soares, Cleonice Creusa dos Santos, Luciano Vasconcellos Pacheco, Ivanilson Pimenta Santos, Tatiana Barbosa dos Santos Magalhães, Milena Botelho Pereira Soares, Elisalva Teixeira Guimarães, Cássio Santana Meira, Silvia Lima Costa, Victor Diógenes Amaral da Silva, Lourenço Luís Botelho de Santana, Aníbal de Freitas Santos Júnior
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
quercetin
synthesis
quercetin pentaacetate
antioxidant
antileishmania
anti-inflammatory
Online Access:https://www.mdpi.com/1420-3049/26/22/6923

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