Clinical characteristics of COVID-19 in young patients differ from middle-aged and elderly patients
Introduction Coronavirus disease-2019 (COVID-19) spreads worldwide. The study aimed to understand the clinical characteristics of young COVID-19 patients. Material and methods Ninety patients with severe COVID-19 infection in western Chongqing were collected from 21 January to 14 March 2020. They w...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2021-03-01
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| Series: | Archives of Medical Science |
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| Online Access: | https://www.archivesofmedicalscience.com/Clinical-characteristics-of-COVID-19-in-young-patients-differ-from-middle-aged-and,133090,0,2.html |
| _version_ | 1811252727593828352 |
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| author | Keqiang Wan Chang Su Lingxi Kong Juan Liao Wenguang Tian Hua Luo |
| author_facet | Keqiang Wan Chang Su Lingxi Kong Juan Liao Wenguang Tian Hua Luo |
| author_sort | Keqiang Wan |
| collection | DOAJ |
| description | Introduction
Coronavirus disease-2019 (COVID-19) spreads worldwide. The study aimed to understand the clinical characteristics of young COVID-19 patients.
Material and methods
Ninety patients with severe COVID-19 infection in western Chongqing were collected from 21 January to 14 March 2020. They were divided into 4 groups based on age: youth ( 60 years). The clinical symptoms, laboratory findings, imaging findings, and treatment effects were compared among the groups.
Results
There were 22, 27, 19, and 22 cases in the youth, middle-aged, middle-elderly, and elderly groups, respectively. There were no significant differences with respect to gender or smoking status among the four groups. The clinical indicators of severe disease in the youth group were significantly different from the other three groups, and included the lymphocyte count (p < 0.001), C-reactive protein level (p = 0.03), interleukin-6 level (p = 0.01), chest computed tomography (CT) findings (p < 0.001), number of mild cases (p = 0.02), education level (p < 0.001), and CD4 + T lymphocyte level (p = 0.02) at the time of admission, and the pneumonia severity index (PSI) at the time of discharge (p < 0.001). The complications (p < 0.001) among the youth group were also significantly different from the other groups.
Conclusions
Young patients have milder clinical manifestations, which may be related to higher education level, higher awareness and higher acceptance of the prevention and control of the COVID-19 epidemic, as well as their good immune function. |
| first_indexed | 2024-04-12T16:40:00Z |
| format | Article |
| id | doaj.art-00143ebf3ac541ec899cbf2f747f266f |
| institution | Directory Open Access Journal |
| issn | 1734-1922 1896-9151 |
| language | English |
| last_indexed | 2024-04-12T16:40:00Z |
| publishDate | 2021-03-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj.art-00143ebf3ac541ec899cbf2f747f266f2022-12-22T03:24:50ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512021-03-0118370471010.5114/aoms/133090133090Clinical characteristics of COVID-19 in young patients differ from middle-aged and elderly patientsKeqiang Wan0Chang Su1Lingxi Kong2Juan Liao3Wenguang Tian4Hua Luo5Department of Infectious Diseases, YongChuan Hospital of Chongqing Medical University, ChinaDepartment of Infectious Diseases, YongChuan Hospital of Chongqing Medical University, ChinaDepartment of Infectious Diseases, YongChuan Hospital of Chongqing Medical University, ChinaCentral Laboratory, YongChuan Hospital of Chongqing Medical University, ChinaDepartment of Infectious Diseases, YongChuan Hospital of Chongqing Medical University, ChinaDepartment of Respiratory and Critical Care Medicine, YongChuan Hospital of Chongqing Medical University, ChinaIntroduction Coronavirus disease-2019 (COVID-19) spreads worldwide. The study aimed to understand the clinical characteristics of young COVID-19 patients. Material and methods Ninety patients with severe COVID-19 infection in western Chongqing were collected from 21 January to 14 March 2020. They were divided into 4 groups based on age: youth ( 60 years). The clinical symptoms, laboratory findings, imaging findings, and treatment effects were compared among the groups. Results There were 22, 27, 19, and 22 cases in the youth, middle-aged, middle-elderly, and elderly groups, respectively. There were no significant differences with respect to gender or smoking status among the four groups. The clinical indicators of severe disease in the youth group were significantly different from the other three groups, and included the lymphocyte count (p < 0.001), C-reactive protein level (p = 0.03), interleukin-6 level (p = 0.01), chest computed tomography (CT) findings (p < 0.001), number of mild cases (p = 0.02), education level (p < 0.001), and CD4 + T lymphocyte level (p = 0.02) at the time of admission, and the pneumonia severity index (PSI) at the time of discharge (p < 0.001). The complications (p < 0.001) among the youth group were also significantly different from the other groups. Conclusions Young patients have milder clinical manifestations, which may be related to higher education level, higher awareness and higher acceptance of the prevention and control of the COVID-19 epidemic, as well as their good immune function.https://www.archivesofmedicalscience.com/Clinical-characteristics-of-COVID-19-in-young-patients-differ-from-middle-aged-and,133090,0,2.htmlcovid-19western chongqingyoung patientsclinical characteristics |
| spellingShingle | Keqiang Wan Chang Su Lingxi Kong Juan Liao Wenguang Tian Hua Luo Clinical characteristics of COVID-19 in young patients differ from middle-aged and elderly patients Archives of Medical Science covid-19 western chongqing young patients clinical characteristics |
| title | Clinical characteristics of COVID-19 in young patients differ from middle-aged and elderly patients |
| title_full | Clinical characteristics of COVID-19 in young patients differ from middle-aged and elderly patients |
| title_fullStr | Clinical characteristics of COVID-19 in young patients differ from middle-aged and elderly patients |
| title_full_unstemmed | Clinical characteristics of COVID-19 in young patients differ from middle-aged and elderly patients |
| title_short | Clinical characteristics of COVID-19 in young patients differ from middle-aged and elderly patients |
| title_sort | clinical characteristics of covid 19 in young patients differ from middle aged and elderly patients |
| topic | covid-19 western chongqing young patients clinical characteristics |
| url | https://www.archivesofmedicalscience.com/Clinical-characteristics-of-COVID-19-in-young-patients-differ-from-middle-aged-and,133090,0,2.html |
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