Molecular Dynamics and In Vitro Studies Elucidating the Tunable Features of Reconfigurable Nanodiscs for Guiding the Optimal Design of Curcumin Formulation

Molecular Dynamics and In Vitro Studies Elucidating the Tunable Features of Reconfigurable Nanodiscs for Guiding the Optimal Design of Curcumin Formulation

In this study, we advance our exploration of Apolipoprotein A-I (apoA-I) peptide analogs (APAs) for their application in nanodisc (ND) assembly, focusing on the dynamic conformational characteristics and the potential for drug delivery. We explore APA-ND interactions with an emphasis on curcumin enc...

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Bibliographic Details
Main Authors: Yongxiao Li, Wanting Xu, Xinpei Wang, Ruizhi Lai, Xiaohui Qiu, Zekai Zeng, Zhe Wang, Junqing Wang
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Bioengineering
Subjects:
NDs
curcumin
apoA-I
lipid bilayer
membrane
anticancer
Online Access:https://www.mdpi.com/2306-5354/11/3/245

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