Radio(chemo)therapy in locally advanced nonsmall cell lung cancer
Definitive radiochemotherapy is the standard treatment for many patients with locally advanced nonsmall cell lung cancer (NSCLC). Treatment outcomes have improved over the last decades. Several treatment regimens have been shown effective and safe. This review summarises the results of significant s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2016-03-01
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| Series: | European Respiratory Review |
| Online Access: | http://err.ersjournals.com/content/25/139/65.full |
| _version_ | 1828916650088333312 |
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| author | Markus Glatzer Olgun Elicin Sara Ramella Ursula Nestle Paul Martin Putora |
| author_facet | Markus Glatzer Olgun Elicin Sara Ramella Ursula Nestle Paul Martin Putora |
| author_sort | Markus Glatzer |
| collection | DOAJ |
| description | Definitive radiochemotherapy is the standard treatment for many patients with locally advanced nonsmall cell lung cancer (NSCLC). Treatment outcomes have improved over the last decades. Several treatment regimens have been shown effective and safe. This review summarises the results of significant studies between 1996 and 2015 on concomitant and sequential radiochemotherapy regimens and radiation dose per fraction. Beside therapy regimens, optimised radiotherapy planning is indispensable to improve outcome and minimise radiation-induced toxicity. An insight into the rationale of radiotherapy planning for stage III NSCLC is also provided. |
| first_indexed | 2024-12-13T20:36:45Z |
| format | Article |
| id | doaj.art-001735d50a864a72af1c45313ff70f1f |
| institution | Directory Open Access Journal |
| issn | 0905-9180 1600-0617 |
| language | English |
| last_indexed | 2024-12-13T20:36:45Z |
| publishDate | 2016-03-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | European Respiratory Review |
| spelling | doaj.art-001735d50a864a72af1c45313ff70f1f2022-12-21T23:32:16ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172016-03-0125139657010.1183/16000617.0053-20150053-2015Radio(chemo)therapy in locally advanced nonsmall cell lung cancerMarkus Glatzer0Olgun Elicin1Sara Ramella2Ursula Nestle3Paul Martin Putora4 Dept of Radiation Oncology, Kantonsspital St. Gallen, St. Gallen, Switzerland Dept of Radiation Oncology, University Hospital Bern, Bern, Switzerland Dept of Radiation Oncology, Campus Bio-Medico University, Rome, Italy Dept of Radiation Oncology, University Medical Center Freiburg, Freiburg, Germany Dept of Radiation Oncology, Kantonsspital St. Gallen, St. Gallen, Switzerland Definitive radiochemotherapy is the standard treatment for many patients with locally advanced nonsmall cell lung cancer (NSCLC). Treatment outcomes have improved over the last decades. Several treatment regimens have been shown effective and safe. This review summarises the results of significant studies between 1996 and 2015 on concomitant and sequential radiochemotherapy regimens and radiation dose per fraction. Beside therapy regimens, optimised radiotherapy planning is indispensable to improve outcome and minimise radiation-induced toxicity. An insight into the rationale of radiotherapy planning for stage III NSCLC is also provided.http://err.ersjournals.com/content/25/139/65.full |
| spellingShingle | Markus Glatzer Olgun Elicin Sara Ramella Ursula Nestle Paul Martin Putora Radio(chemo)therapy in locally advanced nonsmall cell lung cancer European Respiratory Review |
| title | Radio(chemo)therapy in locally advanced nonsmall cell lung cancer |
| title_full | Radio(chemo)therapy in locally advanced nonsmall cell lung cancer |
| title_fullStr | Radio(chemo)therapy in locally advanced nonsmall cell lung cancer |
| title_full_unstemmed | Radio(chemo)therapy in locally advanced nonsmall cell lung cancer |
| title_short | Radio(chemo)therapy in locally advanced nonsmall cell lung cancer |
| title_sort | radio chemo therapy in locally advanced nonsmall cell lung cancer |
| url | http://err.ersjournals.com/content/25/139/65.full |
| work_keys_str_mv | AT markusglatzer radiochemotherapyinlocallyadvancednonsmallcelllungcancer AT olgunelicin radiochemotherapyinlocallyadvancednonsmallcelllungcancer AT sararamella radiochemotherapyinlocallyadvancednonsmallcelllungcancer AT ursulanestle radiochemotherapyinlocallyadvancednonsmallcelllungcancer AT paulmartinputora radiochemotherapyinlocallyadvancednonsmallcelllungcancer |