Coexisting Pituitary Adenoma and Suprasellar Meningioma: A Coincidence or Causation Effect? Report of Two Cases and Review of Literature

Background and Importance: The coexistence of pituitary adenoma and another type of brain tumor is a very rare clinical scenario. Even though such a presentation can be an incidental event but the possible pathogenesis of coexistence of different lesions in the sella and suprasellar region has not y...

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Main Authors: Seyed-Abolghasem Mortazavi, Mohamad Shirani, Saeed Saeedinia, Reza Sanjari, Hamed Hanif, Abbas Amirjamshidi
Format: Article
Language:English
Published: Guilan University of Medical Sciences 2015-06-01
Series:Iranian Journal of Neurosurgery
Subjects:
Online Access:http://irjns.org/browse.php?a_code=A-10-100-16&slc_lang=en&sid=1
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author Seyed-Abolghasem Mortazavi
Mohamad Shirani
Saeed Saeedinia
Reza Sanjari
Hamed Hanif
Abbas Amirjamshidi
author_facet Seyed-Abolghasem Mortazavi
Mohamad Shirani
Saeed Saeedinia
Reza Sanjari
Hamed Hanif
Abbas Amirjamshidi
author_sort Seyed-Abolghasem Mortazavi
collection DOAJ
description Background and Importance: The coexistence of pituitary adenoma and another type of brain tumor is a very rare clinical scenario. Even though such a presentation can be an incidental event but the possible pathogenesis of coexistence of different lesions in the sella and suprasellar region has not yet been elucidated. Case Presentation: Two cases of concomitant sellar and suprasellar region tumors are reported. A 37-year-old lady with Prolactinoma and a suprasellar meningioma and a 42-year-old Acromegalic man with suprasellar meningioma and a pituitary adenoma (PA). Conclusion: Both meningiomas were removed transcranially while the Prolactinoma could be managed medically and the growth hormone (GH) secreting adenoma was removed trans-sphenoidally. The visual problems and hormonal imbalances of both patients improved postoperatively and there has been no sign of recurrence of the lesions after a mean of five years follow up. The literature is reviewed on this topic and the possible pathogenesis and management protocol of similar lesions are discussed.
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spelling doaj.art-001764142aad4d198e5ad4b8e1dfcb2e2022-12-21T23:44:38ZengGuilan University of Medical SciencesIranian Journal of Neurosurgery2423-64972423-68292015-06-01114346Coexisting Pituitary Adenoma and Suprasellar Meningioma: A Coincidence or Causation Effect? Report of Two Cases and Review of LiteratureSeyed-Abolghasem Mortazavi0Mohamad Shirani1Saeed Saeedinia2Reza Sanjari3Hamed Hanif4Abbas Amirjamshidi5 Background and Importance: The coexistence of pituitary adenoma and another type of brain tumor is a very rare clinical scenario. Even though such a presentation can be an incidental event but the possible pathogenesis of coexistence of different lesions in the sella and suprasellar region has not yet been elucidated. Case Presentation: Two cases of concomitant sellar and suprasellar region tumors are reported. A 37-year-old lady with Prolactinoma and a suprasellar meningioma and a 42-year-old Acromegalic man with suprasellar meningioma and a pituitary adenoma (PA). Conclusion: Both meningiomas were removed transcranially while the Prolactinoma could be managed medically and the growth hormone (GH) secreting adenoma was removed trans-sphenoidally. The visual problems and hormonal imbalances of both patients improved postoperatively and there has been no sign of recurrence of the lesions after a mean of five years follow up. The literature is reviewed on this topic and the possible pathogenesis and management protocol of similar lesions are discussed.http://irjns.org/browse.php?a_code=A-10-100-16&slc_lang=en&sid=1AcromegalyMultiple primary brain tumorProlactinomaSuprasellar meningiomaPituitary adenoma
spellingShingle Seyed-Abolghasem Mortazavi
Mohamad Shirani
Saeed Saeedinia
Reza Sanjari
Hamed Hanif
Abbas Amirjamshidi
Coexisting Pituitary Adenoma and Suprasellar Meningioma: A Coincidence or Causation Effect? Report of Two Cases and Review of Literature
Iranian Journal of Neurosurgery
Acromegaly
Multiple primary brain tumor
Prolactinoma
Suprasellar meningioma
Pituitary adenoma
title Coexisting Pituitary Adenoma and Suprasellar Meningioma: A Coincidence or Causation Effect? Report of Two Cases and Review of Literature
title_full Coexisting Pituitary Adenoma and Suprasellar Meningioma: A Coincidence or Causation Effect? Report of Two Cases and Review of Literature
title_fullStr Coexisting Pituitary Adenoma and Suprasellar Meningioma: A Coincidence or Causation Effect? Report of Two Cases and Review of Literature
title_full_unstemmed Coexisting Pituitary Adenoma and Suprasellar Meningioma: A Coincidence or Causation Effect? Report of Two Cases and Review of Literature
title_short Coexisting Pituitary Adenoma and Suprasellar Meningioma: A Coincidence or Causation Effect? Report of Two Cases and Review of Literature
title_sort coexisting pituitary adenoma and suprasellar meningioma a coincidence or causation effect report of two cases and review of literature
topic Acromegaly
Multiple primary brain tumor
Prolactinoma
Suprasellar meningioma
Pituitary adenoma
url http://irjns.org/browse.php?a_code=A-10-100-16&slc_lang=en&sid=1
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