Current Views about the Inflammatory Damage Triggered by Bacterial Superantigens and Experimental Attempts to Neutralize Superantigen-Mediated Toxic Effects with Natural and Biological Products

Current Views about the Inflammatory Damage Triggered by Bacterial Superantigens and Experimental Attempts to Neutralize Superantigen-Mediated Toxic Effects with Natural and Biological Products

Superantigens, i.e., staphylococcal enterotoxins and toxic shock syndrome toxin-1, interact with T cells in a different manner in comparison to conventional antigens. In fact, they activate a larger contingent of T lymphocytes, binding outside the peptide-binding groove of the major histocompatibili...

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Bibliographic Details
Main Authors: Luigi Santacroce, Skender Topi, Ioannis Alexandros Charitos, Roberto Lovero, Paolo Luperto, Raffaele Palmirotta, Emilio Jirillo
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pathophysiology
Subjects:
superantigens
toxic shock syndrome (TSS)
immune response
antimicrobial peptides
beta-glucans
cytokines
Online Access:https://www.mdpi.com/1873-149X/31/1/2

Internet

https://www.mdpi.com/1873-149X/31/1/2

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