N-Acetyl Cysteine Inhibits Endothelin-1-Induced ROS Dependent Cardiac Hypertrophy through Superoxide Dismutase Regulation

N-Acetyl Cysteine Inhibits Endothelin-1-Induced ROS Dependent Cardiac Hypertrophy through Superoxide Dismutase Regulation

Objective: Oxidative stress down regulates antioxidant enzymes including superoxide dismutase (SOD) and contributes to the development of cardiac hypertrophy. N-Acetyl cysteine (NAC) can enhance the SOD activity, so the aim of this study is to highlight the inhibitory role of NAC against endothel...

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Bibliographic Details
Main Authors: Sobia Mushtaq, Tahir Ali, Qamar Javed, Sobia Tabassum, Iram Murtaza
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2015-07-01
Series:Cell Journal
Subjects:
Cardiac Hypertrophy
Endothelin-1
Oxidative Stress
Superoxide Dismutase
Reactive Oxygen Species
Online Access:http://celljournal.org/web/journal/article/391/download

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