A systematic review of factors associated with outcome of psychological treatments for post-traumatic stress disorder

Objective Psychological interventions for post-traumatic stress disorder (PTSD) are not always effective and can leave some individuals with enduring symptoms. Little is known about factors that are associated with better or worse treatment outcome. Our objective was to address this gap. Method We u...

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Main Authors: Kali S. Barawi, Catrin Lewis, Natalie Simon, Jonathan I. Bisson
Format: Article
Language:English
Published: Taylor & Francis Group 2020-12-01
Series:European Journal of Psychotraumatology
Subjects:
Online Access:http://dx.doi.org/10.1080/20008198.2020.1774240
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author Kali S. Barawi
Catrin Lewis
Natalie Simon
Jonathan I. Bisson
author_facet Kali S. Barawi
Catrin Lewis
Natalie Simon
Jonathan I. Bisson
author_sort Kali S. Barawi
collection DOAJ
description Objective Psychological interventions for post-traumatic stress disorder (PTSD) are not always effective and can leave some individuals with enduring symptoms. Little is known about factors that are associated with better or worse treatment outcome. Our objective was to address this gap. Method We undertook a systematic review following Cochrane Collaboration Guidelines. We included 126 randomized controlled trials (RCTs) of psychological interventions for PTSD and examined factors that were associated with treatment outcome, in terms of severity of PTSD symptoms post-treatment, and recovery or remission. Results Associations were neither consistent nor strong. Two factors were associated with smaller reductions in severity of PTSD symptoms post-treatment: comorbid diagnosis of depression, and higher PTSD symptom severity at baseline assessment. Higher education, adherence to homework and experience of a more recent trauma were associated with better treatment outcome. Conclusion Identifying and understanding why certain factors are associated with treatment outcome is vital to determine which individuals are most likely to benefit from particular treatments and to develop more effective treatments in the future. There is an urgent need for consistent and standardized reporting of factors associated with treatment outcome in all clinical trials.
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spelling doaj.art-0024ab1000f44c96a31682dfda5d300d2023-01-12T15:31:32ZengTaylor & Francis GroupEuropean Journal of Psychotraumatology2000-80662020-12-0111110.1080/20008198.2020.17742401774240A systematic review of factors associated with outcome of psychological treatments for post-traumatic stress disorderKali S. Barawi0Catrin Lewis1Natalie Simon2Jonathan I. Bisson3Cardiff University School of MedicineCardiff University School of MedicineCardiff University School of MedicineCardiff University School of MedicineObjective Psychological interventions for post-traumatic stress disorder (PTSD) are not always effective and can leave some individuals with enduring symptoms. Little is known about factors that are associated with better or worse treatment outcome. Our objective was to address this gap. Method We undertook a systematic review following Cochrane Collaboration Guidelines. We included 126 randomized controlled trials (RCTs) of psychological interventions for PTSD and examined factors that were associated with treatment outcome, in terms of severity of PTSD symptoms post-treatment, and recovery or remission. Results Associations were neither consistent nor strong. Two factors were associated with smaller reductions in severity of PTSD symptoms post-treatment: comorbid diagnosis of depression, and higher PTSD symptom severity at baseline assessment. Higher education, adherence to homework and experience of a more recent trauma were associated with better treatment outcome. Conclusion Identifying and understanding why certain factors are associated with treatment outcome is vital to determine which individuals are most likely to benefit from particular treatments and to develop more effective treatments in the future. There is an urgent need for consistent and standardized reporting of factors associated with treatment outcome in all clinical trials.http://dx.doi.org/10.1080/20008198.2020.1774240psychological interventionrandomized control trialpost-traumatic stress disordertreatment outcome
spellingShingle Kali S. Barawi
Catrin Lewis
Natalie Simon
Jonathan I. Bisson
A systematic review of factors associated with outcome of psychological treatments for post-traumatic stress disorder
European Journal of Psychotraumatology
psychological intervention
randomized control trial
post-traumatic stress disorder
treatment outcome
title A systematic review of factors associated with outcome of psychological treatments for post-traumatic stress disorder
title_full A systematic review of factors associated with outcome of psychological treatments for post-traumatic stress disorder
title_fullStr A systematic review of factors associated with outcome of psychological treatments for post-traumatic stress disorder
title_full_unstemmed A systematic review of factors associated with outcome of psychological treatments for post-traumatic stress disorder
title_short A systematic review of factors associated with outcome of psychological treatments for post-traumatic stress disorder
title_sort systematic review of factors associated with outcome of psychological treatments for post traumatic stress disorder
topic psychological intervention
randomized control trial
post-traumatic stress disorder
treatment outcome
url http://dx.doi.org/10.1080/20008198.2020.1774240
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