Cell-specific expression of the FAP gene is regulated by enhancer elements

Cell-specific expression of the FAP gene is regulated by enhancer elements

Fibroblast activation protein (FAP) is an integral membrane serine protease that acts as both dipeptidyl peptidase and collagenase. In recent years, FAP has attracted considerable attention due to its specific upregulation in multiple types of tumor cell populations, including cancer cells in variou...

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Bibliographic Details
Main Authors: Dina V. Antonova, Dmitry A. Gnatenko, Elena S. Kotova, Victor V. Pleshkan, Alexey I. Kuzmich, Dmitry A. Didych, Eugene D. Sverdlov, Irina V. Alekseenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
fibroblast activation protein alpha
FAP
enhancer
promoter
H3K27ac
stat3
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1111511/full

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