The Preferential Use of Anakinra in Various Settings of FMF: A Review Applied to an Updated Treatment-Related Perspective of the Disease

The Preferential Use of Anakinra in Various Settings of FMF: A Review Applied to an Updated Treatment-Related Perspective of the Disease

Familial Mediterranean fever (FMF), the most frequent monogenic autoinflammatory disease, is manifested with recurrent and chronic inflammation and amyloid A (AA) amyloidosis, driven by overproduction of interleukin 1 (IL-1) through an activated pyrin inflammasome. Consequently, non-responsiveness t...

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Bibliographic Details
Main Authors: Eitan Giat, Ilan Ben-Zvi, Merav Lidar, Avi Livneh
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
familial Mediterranean fever (FMF)
anakinra
interleukin 1 blockers
colchicine failure
AA amyloidosis
exertional leg pain
Online Access:https://www.mdpi.com/1422-0067/23/7/3956

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