Case report of the first laparoscopic adrenalectomy treatment of pheochromocytoma in pediatric population in Republic of Serbia
Pheochromocytoma is a tumor that arises from adrenal medulla and it is characterized by increased secretion of catecholamines. The incidence of pheochromocytoma is 3 to 8 cases per million inhabitants, of which about 10 to 20% of diagnosed pheochromocytomas occurs in the pediatric population, with a...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Specijalna bolnica za bolesti štitaste žlezde i bolesti metabolizma Zlatibor
2022-01-01
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| Series: | Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor" |
| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1821-1925/2022/1821-19252284007J.pdf |
| _version_ | 1818264425982853120 |
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| author | Jovanović Milan Paunović Ivan Zdravković Vera Buzejić Matija Odalović Božidar Zorić Goran Slijepčević Nikola Taušanović Katarina Rovčanin Branislav Vučen Duška Stepanović Boban Ilić Jovan Parezanović Milan Bulatović Danilo Živaljević Vladan |
| author_facet | Jovanović Milan Paunović Ivan Zdravković Vera Buzejić Matija Odalović Božidar Zorić Goran Slijepčević Nikola Taušanović Katarina Rovčanin Branislav Vučen Duška Stepanović Boban Ilić Jovan Parezanović Milan Bulatović Danilo Živaljević Vladan |
| author_sort | Jovanović Milan |
| collection | DOAJ |
| description | Pheochromocytoma is a tumor that arises from adrenal medulla and it is characterized by increased secretion of catecholamines. The incidence of pheochromocytoma is 3 to 8 cases per million inhabitants, of which about 10 to 20% of diagnosed pheochromocytomas occurs in the pediatric population, with a higher frequency in boys. In 1.7% of the pediatric population with hypertension, the cause of hypertension is pheochromocytoma. Due to headaches and verified hypertension on twenty-four-hour holter blood pressure monitoring, the 13-year-old female patient underwent ultrasound, followed by scintigraphy and magnetic resonance imaging of the abdomen, which described an oval change above the right kidney about 4.5 cm in diameter suspected of pheochromocytoma. Twenty-four-hour urine cateholamines showed elevated noradrenaline values as much as 45 times higher than the reference range, as well as elevated Dopamine values. After adequate preparation with phenoxybenzamine and bisoprolol for two weeks, a right laparoscopic adrenalectomy was performed at the University Children's Clinic in Tirsova, which is also the first operation of this type in the pediatric population. Intraoperatively, the maximum value of tension was 180/120 mmHg. Pathohistological findings confirmed pheochromocytoma. Although a rare cause of hypertension in the pediatric population, young patients with newly diagnosed hypertension should be examined for possible pheochromocytoma. Laparoscopic adrenalectomy through both the lateral transabdominal and posterior retroperitoneoscopic approach is the gold standard for the treatment of pheochromocytomas in both the adult and pediatric populations. |
| first_indexed | 2024-12-12T19:34:43Z |
| format | Article |
| id | doaj.art-002ff2715bf14194958afde076e5e12e |
| institution | Directory Open Access Journal |
| issn | 1821-1925 2406-131X |
| language | English |
| last_indexed | 2024-12-12T19:34:43Z |
| publishDate | 2022-01-01 |
| publisher | Specijalna bolnica za bolesti štitaste žlezde i bolesti metabolizma Zlatibor |
| record_format | Article |
| series | Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor" |
| spelling | doaj.art-002ff2715bf14194958afde076e5e12e2022-12-22T00:14:20ZengSpecijalna bolnica za bolesti štitaste žlezde i bolesti metabolizma ZlatiborMedicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor"1821-19252406-131X2022-01-01278472510.5937/mgiszm2284007J1821-19252284007JCase report of the first laparoscopic adrenalectomy treatment of pheochromocytoma in pediatric population in Republic of SerbiaJovanović Milan0https://orcid.org/0000-0002-0118-8450Paunović Ivan1Zdravković Vera2Buzejić Matija3https://orcid.org/0000-0001-5580-3247Odalović Božidar4Zorić Goran5Slijepčević Nikola6https://orcid.org/0000-0002-3999-1062Taušanović Katarina7https://orcid.org/0000-0002-6793-046XRovčanin Branislav8https://orcid.org/0000-0002-8099-3764Vučen Duška9https://orcid.org/0000-0002-7495-4590Stepanović Boban10Ilić Jovan11Parezanović Milan12Bulatović Danilo13Živaljević Vladan14https://orcid.org/0000-0002-6661-6751Univerzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaMedicinski fakultet Univerziteta u Beogradu, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaUniverzitetski klinički centar Srbije, Centar za endokrinu hirurgiju, SerbiaPheochromocytoma is a tumor that arises from adrenal medulla and it is characterized by increased secretion of catecholamines. The incidence of pheochromocytoma is 3 to 8 cases per million inhabitants, of which about 10 to 20% of diagnosed pheochromocytomas occurs in the pediatric population, with a higher frequency in boys. In 1.7% of the pediatric population with hypertension, the cause of hypertension is pheochromocytoma. Due to headaches and verified hypertension on twenty-four-hour holter blood pressure monitoring, the 13-year-old female patient underwent ultrasound, followed by scintigraphy and magnetic resonance imaging of the abdomen, which described an oval change above the right kidney about 4.5 cm in diameter suspected of pheochromocytoma. Twenty-four-hour urine cateholamines showed elevated noradrenaline values as much as 45 times higher than the reference range, as well as elevated Dopamine values. After adequate preparation with phenoxybenzamine and bisoprolol for two weeks, a right laparoscopic adrenalectomy was performed at the University Children's Clinic in Tirsova, which is also the first operation of this type in the pediatric population. Intraoperatively, the maximum value of tension was 180/120 mmHg. Pathohistological findings confirmed pheochromocytoma. Although a rare cause of hypertension in the pediatric population, young patients with newly diagnosed hypertension should be examined for possible pheochromocytoma. Laparoscopic adrenalectomy through both the lateral transabdominal and posterior retroperitoneoscopic approach is the gold standard for the treatment of pheochromocytomas in both the adult and pediatric populations.https://scindeks-clanci.ceon.rs/data/pdf/1821-1925/2022/1821-19252284007J.pdf |
| spellingShingle | Jovanović Milan Paunović Ivan Zdravković Vera Buzejić Matija Odalović Božidar Zorić Goran Slijepčević Nikola Taušanović Katarina Rovčanin Branislav Vučen Duška Stepanović Boban Ilić Jovan Parezanović Milan Bulatović Danilo Živaljević Vladan Case report of the first laparoscopic adrenalectomy treatment of pheochromocytoma in pediatric population in Republic of Serbia Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor" |
| title | Case report of the first laparoscopic adrenalectomy treatment of pheochromocytoma in pediatric population in Republic of Serbia |
| title_full | Case report of the first laparoscopic adrenalectomy treatment of pheochromocytoma in pediatric population in Republic of Serbia |
| title_fullStr | Case report of the first laparoscopic adrenalectomy treatment of pheochromocytoma in pediatric population in Republic of Serbia |
| title_full_unstemmed | Case report of the first laparoscopic adrenalectomy treatment of pheochromocytoma in pediatric population in Republic of Serbia |
| title_short | Case report of the first laparoscopic adrenalectomy treatment of pheochromocytoma in pediatric population in Republic of Serbia |
| title_sort | case report of the first laparoscopic adrenalectomy treatment of pheochromocytoma in pediatric population in republic of serbia |
| url | https://scindeks-clanci.ceon.rs/data/pdf/1821-1925/2022/1821-19252284007J.pdf |
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