TIPE2 deletion improves the therapeutic potential of adoptively transferred NK cells

TIPE2 deletion improves the therapeutic potential of adoptively transferred NK cells

Background To enhance the efficacy of adoptive NK cell therapy against solid tumors, NK cells must be modified to resist exhaustion in the tumor microenvironment (TME). However, the molecular checkpoint underlying NK cell exhaustion in the TME remains elusive.Methods We analyzed the correlation betw...

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Bibliographic Details
Main Authors:	Zhigang Tian, Xiaohu Zheng, Yingying Huang, Jiacheng Bi, Xiaomeng Jin, Chaoyue Zheng, Haoyu Sun
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2023-02-01
Series:	Journal for ImmunoTherapy of Cancer
Online Access:	https://jitc.bmj.com/content/11/2/e006002.full

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