Identification of Transcription Factors Regulating SARS-CoV-2 Tropism Factor Expression by Inferring Cell-Type-Specific Transcriptional Regulatory Networks in Human Lungs

Identification of Transcription Factors Regulating SARS-CoV-2 Tropism Factor Expression by Inferring Cell-Type-Specific Transcriptional Regulatory Networks in Human Lungs

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that caused the coronavirus disease 2019 (COVID-19) pandemic. Though previous studies have suggested that SARS-CoV-2 cellular tropism depends on the host-cell-expressed proteins, whether transcriptional regulation controls SAR...

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Bibliographic Details
Main Authors: Haonan Tong, Hao Chen, Cranos M. Williams
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Viruses
Subjects:
SARS-CoV-2
single-cell RNA-seq
differential network analysis
Online Access:https://www.mdpi.com/1999-4915/14/4/837

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https://www.mdpi.com/1999-4915/14/4/837

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