Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3

Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3

Objective: Regulation of proteasomal activity is an essential component of cellular proteostasis and function. This is evident in patients with mutations in proteasome subunits and associated regulators, who suffer from proteasome-associated autoinflammatory syndromes (PRAAS). These patients display...

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Bibliographic Details
Main Authors: Nienke Willemsen, Isabel Arigoni, Maja Studencka-Turski, Elke Krüger, Alexander Bartelt
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Molecular Metabolism
Subjects:
brown adipose tissue
Adipocytes
Proteasome
Ubiquitin
Proteostasis
PSMB4
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822000874

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http://www.sciencedirect.com/science/article/pii/S2212877822000874

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