GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming

GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming

Levo-dihydroxyphenylalanine (L-DOPA) is the most effective treatment for Parkinson's disease; however, most patients develop uncontrollable abnormal involuntary movements known as L-DOPA-induced dyskinesia. L-DOPA-induced dyskinesia can be reduced by pallidotomy of the medial globus pallidus or...

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Bibliographic Details
Main Authors: Haruo Nishijima, Fumiaki Mori, Akira Arai, Gang Zhu, Koichi Wakabayashi, Motohiro Okada, Shinya Ueno, Noritaka Ichinohe, Chieko Suzuki, Tomoya Kon, Masahiko Tomiyama
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Neurobiology of Disease
Subjects:
Basal ganglia
Deep brain stimulation
Microdialysis
Parkinson's disease
Synaptic transmission
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120302540

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