Single-Case Experimental Designs to Evaluate Novel Technology-Based Health Interventions

Technology-based interventions to promote health are expanding rapidly. Assessing the preliminary efficacy of these interventions can be achieved by employing single-case experiments (sometimes referred to as n-of-1 studies). Although single-case experiments are often misunderstood, they offer excel...

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Main Authors: Dallery, Jesse, Cassidy, Rachel N, Raiff, Bethany R
Format: Article
Language:English
Published: JMIR Publications 2013-02-01
Series:Journal of Medical Internet Research
Online Access:http://www.jmir.org/2013/2/e22/
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author Dallery, Jesse
Cassidy, Rachel N
Raiff, Bethany R
author_facet Dallery, Jesse
Cassidy, Rachel N
Raiff, Bethany R
author_sort Dallery, Jesse
collection DOAJ
description Technology-based interventions to promote health are expanding rapidly. Assessing the preliminary efficacy of these interventions can be achieved by employing single-case experiments (sometimes referred to as n-of-1 studies). Although single-case experiments are often misunderstood, they offer excellent solutions to address the challenges associated with testing new technology-based interventions. This paper provides an introduction to single-case techniques and highlights advances in developing and evaluating single-case experiments, which help ensure that treatment outcomes are reliable, replicable, and generalizable. These advances include quality control standards, heuristics to guide visual analysis of time-series data, effect size calculations, and statistical analyses. They also include experimental designs to isolate the active elements in a treatment package and to assess the mechanisms of behavior change. The paper concludes with a discussion of issues related to the generality of findings derived from single-case research and how generality can be established through replication and through analysis of behavioral mechanisms.
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spelling doaj.art-003300f8fe8c402e80197968ad134a392022-12-21T20:16:01ZengJMIR PublicationsJournal of Medical Internet Research1438-88712013-02-01152e2210.2196/jmir.2227Single-Case Experimental Designs to Evaluate Novel Technology-Based Health InterventionsDallery, JesseCassidy, Rachel NRaiff, Bethany RTechnology-based interventions to promote health are expanding rapidly. Assessing the preliminary efficacy of these interventions can be achieved by employing single-case experiments (sometimes referred to as n-of-1 studies). Although single-case experiments are often misunderstood, they offer excellent solutions to address the challenges associated with testing new technology-based interventions. This paper provides an introduction to single-case techniques and highlights advances in developing and evaluating single-case experiments, which help ensure that treatment outcomes are reliable, replicable, and generalizable. These advances include quality control standards, heuristics to guide visual analysis of time-series data, effect size calculations, and statistical analyses. They also include experimental designs to isolate the active elements in a treatment package and to assess the mechanisms of behavior change. The paper concludes with a discussion of issues related to the generality of findings derived from single-case research and how generality can be established through replication and through analysis of behavioral mechanisms.http://www.jmir.org/2013/2/e22/
spellingShingle Dallery, Jesse
Cassidy, Rachel N
Raiff, Bethany R
Single-Case Experimental Designs to Evaluate Novel Technology-Based Health Interventions
Journal of Medical Internet Research
title Single-Case Experimental Designs to Evaluate Novel Technology-Based Health Interventions
title_full Single-Case Experimental Designs to Evaluate Novel Technology-Based Health Interventions
title_fullStr Single-Case Experimental Designs to Evaluate Novel Technology-Based Health Interventions
title_full_unstemmed Single-Case Experimental Designs to Evaluate Novel Technology-Based Health Interventions
title_short Single-Case Experimental Designs to Evaluate Novel Technology-Based Health Interventions
title_sort single case experimental designs to evaluate novel technology based health interventions
url http://www.jmir.org/2013/2/e22/
work_keys_str_mv AT dalleryjesse singlecaseexperimentaldesignstoevaluatenoveltechnologybasedhealthinterventions
AT cassidyracheln singlecaseexperimentaldesignstoevaluatenoveltechnologybasedhealthinterventions
AT raiffbethanyr singlecaseexperimentaldesignstoevaluatenoveltechnologybasedhealthinterventions