Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature

Myeloid sarcoma or granulocytic sarcoma (GS) is a rare disease with poor prognosis. It is characterized by the occurrence of tumor masses at an extra-medullary tissue. It is composed of myeloblastic cells and usually occurs in association with acute myeloid leukemia. Because of its nonspecific clini...

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Main Authors: Mozaffar Aznab, Naser Kamalian, Omid Beiki, Farhad Naleini
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-03-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/395
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author Mozaffar Aznab
Naser Kamalian
Omid Beiki
Farhad Naleini
author_facet Mozaffar Aznab
Naser Kamalian
Omid Beiki
Farhad Naleini
author_sort Mozaffar Aznab
collection DOAJ
description Myeloid sarcoma or granulocytic sarcoma (GS) is a rare disease with poor prognosis. It is characterized by the occurrence of tumor masses at an extra-medullary tissue. It is composed of myeloblastic cells and usually occurs in association with acute myeloid leukemia. Because of its nonspecific clinical and radiologic findings, its diagnosis might be challenging. It might be more commonly found in patients with specific cytogenetic abnormalities, particularly with the t (8; 21) translocation and less frequently the inv (16) type. We report a case of GS in a 62 years old man without particular previous pathologies, which brutally presented as an ascites and generalized edema. The laparoscopy showed involvement of greater omentum and peritoneum. The histologic examination of greater omentum showed granulocytic sarcoma. The bone marrow aspiration was normal. We started treatment of patient by standard acute myeloid leukemia's chemotherapy.
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spelling doaj.art-00357e16b57f4c53a948f18473fb8ae32023-09-02T18:08:23ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-22072015-03-0191381Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literatureMozaffar Aznab0Naser Kamalian1Omid Beiki2Farhad Naleini3Medical Oncologist-Hematologist, Assistant professor, Kermanshah University of Medical Sciences, Kermanshah, Iran.Professors, Tehran University of Medical Sciences, Tehran, Iran.Research Center for Environmental Determinants of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.Assistant professor, Kermanshah, University of Medical Sciences, Kermanshah, Iran.Myeloid sarcoma or granulocytic sarcoma (GS) is a rare disease with poor prognosis. It is characterized by the occurrence of tumor masses at an extra-medullary tissue. It is composed of myeloblastic cells and usually occurs in association with acute myeloid leukemia. Because of its nonspecific clinical and radiologic findings, its diagnosis might be challenging. It might be more commonly found in patients with specific cytogenetic abnormalities, particularly with the t (8; 21) translocation and less frequently the inv (16) type. We report a case of GS in a 62 years old man without particular previous pathologies, which brutally presented as an ascites and generalized edema. The laparoscopy showed involvement of greater omentum and peritoneum. The histologic examination of greater omentum showed granulocytic sarcoma. The bone marrow aspiration was normal. We started treatment of patient by standard acute myeloid leukemia's chemotherapy.https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/395#No Keywords#
spellingShingle Mozaffar Aznab
Naser Kamalian
Omid Beiki
Farhad Naleini
Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature
International Journal of Hematology-Oncology and Stem Cell Research
#No Keywords#
title Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature
title_full Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature
title_fullStr Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature
title_full_unstemmed Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature
title_short Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature
title_sort myeloid sarcoma of the peritoneum at older ages a case report and review of literature
topic #No Keywords#
url https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/395
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AT omidbeiki myeloidsarcomaoftheperitoneumatolderagesacasereportandreviewofliterature
AT farhadnaleini myeloidsarcomaoftheperitoneumatolderagesacasereportandreviewofliterature