Differential impact of the HEN1 homolog HENN-1 on 21U and 26G RNAs in the germline of Caenorhabditis elegans.

Differential impact of the HEN1 homolog HENN-1 on 21U and 26G RNAs in the germline of Caenorhabditis elegans.

RNA interference (RNAi)-related pathways affect gene activity by sequence-specific recruitment of Ago proteins to mRNA target molecules. The sequence specificity of this process stems from small RNA (sRNA) co-factors bound by the Ago protein. Stability of sRNA molecules in some pathways is in part r...

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Bibliographic Details
Main Authors: Leonie M Kamminga, Josien C van Wolfswinkel, Maartje J Luteijn, Lucas J T Kaaij, Marloes P Bagijn, Alexandra Sapetschnig, Eric A Miska, Eugene Berezikov, René F Ketting
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3400576?pdf=render

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