Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms

Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms

Abstract A genetic system, ProTracer, has been recently developed to record cell proliferation in vivo. However, the ProTracer is initiated by an infrequently used recombinase Dre, which limits its broad application for functional studies employing floxed gene alleles. Here we generated Cre-activate...

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Bibliographic Details
Main Authors: Xiuxiu Liu, Maoying Han, Wendong Weng, Yan Li, Wenjuan Pu, Kuo Liu, Xufeng Li, Lingjuan He, Ruilin Sun, Ruling Shen, Yulong He, Dandan Liang, Yi-Han Chen, Qing-Dong Wang, Jan S. Tchorz, Bin Zhou
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-023-00318-y

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