Butyrate Prevents the Pathogenic Anemia‐Inflammation Circuit by Facilitating Macrophage Iron Export

Butyrate Prevents the Pathogenic Anemia‐Inflammation Circuit by Facilitating Macrophage Iron Export

Abstract Most patients with inflammatory bowel disease (IBD) develop anemia, which is attributed to the dysregulation of iron metabolism. Reciprocally, impaired iron homeostasis also aggravates inflammation. How this iron‐mediated, pathogenic anemia‐inflammation crosstalk is regulated in the gut rem...

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Bibliographic Details
Main Authors: Peng Xiao, Xuechun Cai, Zhou Zhang, Ke Guo, Yuehai Ke, Ziwei Hu, Zhangfa Song, Yuening Zhao, Lingya Yao, Manlu Shen, Jingyun Li, Youling Huang, Lingna Ye, Lingjie Huang, Yu Zhang, Rongbei Liu, Mengque Xu, Xutao Xu, Yuan Zhao, Qian Cao
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
anemia
butyrate
ferroportin
inflammatory bowel disease
macrophages
Online Access:https://doi.org/10.1002/advs.202306571

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