Mucosal Influenza Vector Vaccine Carrying TB10.4 and HspX Antigens Provides Protection against <i>Mycobacterium tuberculosis</i> in Mice and Guinea Pigs

Mucosal Influenza Vector Vaccine Carrying TB10.4 and HspX Antigens Provides Protection against <i>Mycobacterium tuberculosis</i> in Mice and Guinea Pigs

New strategies providing protection against tuberculosis (TB) are still pending. The airborne nature of Mycobacterium tuberculosis (<i>M.tb)</i> infection assumes that the mucosal delivery of the TB vaccine could be a more promising strategy than the systemic route of immunization. We de...

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Bibliographic Details
Main Authors: Mariia Sergeeva, Ekaterina Romanovskaya-Romanko, Natalia Zabolotnyh, Anastasia Pulkina, Kirill Vasilyev, Anna Polina Shurigina, Janna Buzitskaya, Yana Zabrodskaya, Artem Fadeev, Andrey Vasin, Tatiana I. Vinogradova, Marina A. Stukova
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Vaccines
Subjects:
<i>M. tuberculosis</i> multistage vaccine
TB10.4
HspX
influenza vector
mucosal immunization
Online Access:https://www.mdpi.com/2076-393X/9/4/394

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