Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells.
Sepsis, an amplified immune response to systemic infection, is characterized by a transient cytokine storm followed by chronic immune dysfunction. Consequently, sepsis survivors are highly susceptible to newly introduced infections, suggesting sepsis can influence the function and composition of the...
Main Authors: | Roger R Berton, Patrick W McGonagil, Isaac J Jensen, Tiffany K Ybarra, Gail A Bishop, John T Harty, Thomas S Griffith, Vladimir P Badovinac |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-10-01
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Series: | PLoS Pathogens |
Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011720&type=printable |
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