Haplotype analysis of SERPINE1 gene: Risk for aneurysmal subarachnoid hemorrhage and clinical outcomes

Haplotype analysis of SERPINE1 gene: Risk for aneurysmal subarachnoid hemorrhage and clinical outcomes

Abstract Background Aneurysmal subarachnoid hemorrhage (aSAH) has high fatality and permanent disability rates due to the severe damage to brain cells and inflammation. The SERPINE1 gene that encodes PAI‐1 for the regulation of tissue plasminogen activator is considered an important therapeutic targ...

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Bibliographic Details
Main Authors: Mingkuan Lin, Christoph J. Griessenauer, Robert M. Starke, R. Shane Tubbs, Mohammadali M. Shoja, Paul M. Foreman, Nilesh A. Vyas, Beverly C. Walters, Mark R. Harrigan, Philipp Hendrix, Winfield S. Fisher, Jean‐Francois Pittet, Mali Mathru, Robert H. Lipsky
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
clinical vasospasm
Delayed Cerebral Ischemia
SERPINE1
Subarachnoid Hemorrhage
tissue plasminogen activator
Online Access:https://doi.org/10.1002/mgg3.737

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