Experimental Models to Study Skin Wound Healing with a Focus on Angiogenesis
A large number of models are now available for the investigation of skin wound healing. These can be used to study the processes that take place in a phase-specific manner under both physiological and pathological conditions. Most models focus on wound closure, which is a crucial parameter for wound...
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MDPI AG
2021-08-01
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Online Access: | https://www.mdpi.com/2076-3271/9/3/55 |
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author | Eberhard Grambow Heiko Sorg Christian G. G. Sorg Daniel Strüder |
author_facet | Eberhard Grambow Heiko Sorg Christian G. G. Sorg Daniel Strüder |
author_sort | Eberhard Grambow |
collection | DOAJ |
description | A large number of models are now available for the investigation of skin wound healing. These can be used to study the processes that take place in a phase-specific manner under both physiological and pathological conditions. Most models focus on wound closure, which is a crucial parameter for wound healing. However, vascular supply plays an equally important role and corresponding models for selective or parallel investigation of microcirculation regeneration and angiogenesis are also described. In this review article, we therefore focus on the different levels of investigation of skin wound healing (in vivo to in virtuo) and the investigation of angiogenesis and its parameters. |
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institution | Directory Open Access Journal |
issn | 2076-3271 |
language | English |
last_indexed | 2024-03-10T07:26:39Z |
publishDate | 2021-08-01 |
publisher | MDPI AG |
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series | Medical Sciences |
spelling | doaj.art-003e674b8a0c488ca57f00243fa2ae0b2023-11-22T14:09:44ZengMDPI AGMedical Sciences2076-32712021-08-01935510.3390/medsci9030055Experimental Models to Study Skin Wound Healing with a Focus on AngiogenesisEberhard Grambow0Heiko Sorg1Christian G. G. Sorg2Daniel Strüder3Department of General, Visceral, Thoracic, Vascular and Transplantation Surgery, Rostock University Medical Center, 18057 Rostock, GermanyDepartment of Health, University of Witten/Herdecke, Alfred-Herrhausen-Str. 50, 58455 Witten, GermanyChair of Management and Innovation in Health Care, Department of Management and Entrepreneurship, Faculty of Management, Economics and Society, Witten/Herdecke University, Alfred-Herrhausen-Straße 50, 58455 Witten, GermanyDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery “Otto Körner”, Rostock University Medical Center, 18057 Rostock, GermanyA large number of models are now available for the investigation of skin wound healing. These can be used to study the processes that take place in a phase-specific manner under both physiological and pathological conditions. Most models focus on wound closure, which is a crucial parameter for wound healing. However, vascular supply plays an equally important role and corresponding models for selective or parallel investigation of microcirculation regeneration and angiogenesis are also described. In this review article, we therefore focus on the different levels of investigation of skin wound healing (in vivo to in virtuo) and the investigation of angiogenesis and its parameters.https://www.mdpi.com/2076-3271/9/3/55dorsal skin fold chamberchorion-allantois modelrabbitmouseearin virtuo |
spellingShingle | Eberhard Grambow Heiko Sorg Christian G. G. Sorg Daniel Strüder Experimental Models to Study Skin Wound Healing with a Focus on Angiogenesis Medical Sciences dorsal skin fold chamber chorion-allantois model rabbit mouse ear in virtuo |
title | Experimental Models to Study Skin Wound Healing with a Focus on Angiogenesis |
title_full | Experimental Models to Study Skin Wound Healing with a Focus on Angiogenesis |
title_fullStr | Experimental Models to Study Skin Wound Healing with a Focus on Angiogenesis |
title_full_unstemmed | Experimental Models to Study Skin Wound Healing with a Focus on Angiogenesis |
title_short | Experimental Models to Study Skin Wound Healing with a Focus on Angiogenesis |
title_sort | experimental models to study skin wound healing with a focus on angiogenesis |
topic | dorsal skin fold chamber chorion-allantois model rabbit mouse ear in virtuo |
url | https://www.mdpi.com/2076-3271/9/3/55 |
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