Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil
The Taenia solium cysticercosis affects millions of people worldwide and is considered a public health problem, especially in developing countries. The diagnosis of neurocysticercosis is complex and involves the analysis of epidemiological, clinical, neuroimaging, and immunological host data. Neuroc...
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| Format: | Article |
| Language: | English |
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Elsevier
2018-03-01
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| Series: | Brazilian Journal of Infectious Diseases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1413867017308528 |
| _version_ | 1811204410764689408 |
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| author | Kaliny Xavier da Guarda Julia Maria Costa-Cruz Ivanildes Solange da Costa Barcelos |
| author_facet | Kaliny Xavier da Guarda Julia Maria Costa-Cruz Ivanildes Solange da Costa Barcelos |
| author_sort | Kaliny Xavier da Guarda |
| collection | DOAJ |
| description | The Taenia solium cysticercosis affects millions of people worldwide and is considered a public health problem, especially in developing countries. The diagnosis of neurocysticercosis is complex and involves the analysis of epidemiological, clinical, neuroimaging, and immunological host data. Neurocysticercosis is endemic in Brazil, and is related to the cause of death mainly in the Southeast, South, and Central-West regions. The objective of this study was to determine the seroprevalence of cysticercosis in inhabitants of the city of Jataí, Goiás, in the Central-West region of Brazil from April to August 2012. A total of 529 serum samples were analyzed by enzyme-linked immunosorbent assay for detecting IgG antibodies against T. solium larvae, and Western blotting was used for confirming the diagnosis through the recognition of at least two specific peptides from their serum antibodies. The 351/529 (66.3%) reactive samples were analyzed by enzyme-linked immunosorbent assay and Western blotting confirmed the diagnosis in 73 samples that recognized at least two of the following peptides specific IgG antibodies for cysticercosis: 18, 24, 28–32, 39–42, 47–52, 64–68, and 70 kDa. The seroprevalence of cysticercosis was 13.8% (95% CI 5.9–21.7), demonstrating that the studied area is endemic to this disease. Keywords: Cysticercosis, Taenia solium, Epidemiology, Diagnosis, Brazil |
| first_indexed | 2024-04-12T03:12:44Z |
| format | Article |
| id | doaj.art-0041000550bf4e018d9ec3ee128ec6f5 |
| institution | Directory Open Access Journal |
| issn | 1413-8670 |
| language | English |
| last_indexed | 2024-04-12T03:12:44Z |
| publishDate | 2018-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Infectious Diseases |
| spelling | doaj.art-0041000550bf4e018d9ec3ee128ec6f52022-12-22T03:50:16ZengElsevierBrazilian Journal of Infectious Diseases1413-86702018-03-01222146149Seroprevalence of human cysticercosis in Jataí, Goiás state, BrazilKaliny Xavier da Guarda0Julia Maria Costa-Cruz1Ivanildes Solange da Costa Barcelos2Universidade Federal de Goiás, Laboratório de Imunologia, Jataí, GO, BrazilUniversidade Federal de Uberlândia, Instituto de Ciências Biomédicas, Laboratório de Diagnóstico de Parasitoses, Uberlândia, MG, BrazilUniversidade Federal de Goiás, Laboratório de Imunologia, Jataí, GO, Brazil; Corresponding author.The Taenia solium cysticercosis affects millions of people worldwide and is considered a public health problem, especially in developing countries. The diagnosis of neurocysticercosis is complex and involves the analysis of epidemiological, clinical, neuroimaging, and immunological host data. Neurocysticercosis is endemic in Brazil, and is related to the cause of death mainly in the Southeast, South, and Central-West regions. The objective of this study was to determine the seroprevalence of cysticercosis in inhabitants of the city of Jataí, Goiás, in the Central-West region of Brazil from April to August 2012. A total of 529 serum samples were analyzed by enzyme-linked immunosorbent assay for detecting IgG antibodies against T. solium larvae, and Western blotting was used for confirming the diagnosis through the recognition of at least two specific peptides from their serum antibodies. The 351/529 (66.3%) reactive samples were analyzed by enzyme-linked immunosorbent assay and Western blotting confirmed the diagnosis in 73 samples that recognized at least two of the following peptides specific IgG antibodies for cysticercosis: 18, 24, 28–32, 39–42, 47–52, 64–68, and 70 kDa. The seroprevalence of cysticercosis was 13.8% (95% CI 5.9–21.7), demonstrating that the studied area is endemic to this disease. Keywords: Cysticercosis, Taenia solium, Epidemiology, Diagnosis, Brazilhttp://www.sciencedirect.com/science/article/pii/S1413867017308528 |
| spellingShingle | Kaliny Xavier da Guarda Julia Maria Costa-Cruz Ivanildes Solange da Costa Barcelos Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil Brazilian Journal of Infectious Diseases |
| title | Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| title_full | Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| title_fullStr | Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| title_full_unstemmed | Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| title_short | Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| title_sort | seroprevalence of human cysticercosis in jatai goias state brazil |
| url | http://www.sciencedirect.com/science/article/pii/S1413867017308528 |
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