Maximum-Entropy Models of Sequenced Immune Repertoires Predict Antigen-Antibody Affinity.
The immune system has developed a number of distinct complex mechanisms to shape and control the antibody repertoire. One of these mechanisms, the affinity maturation process, works in an evolutionary-like fashion: after binding to a foreign molecule, the antibody-producing B-cells exhibit a high-fr...
| Hlavní autoři: | , , , |
|---|---|
| Médium: | Článek |
| Jazyk: | English |
| Vydáno: |
Public Library of Science (PLoS)
2016-04-01
|
| Edice: | PLoS Computational Biology |
| On-line přístup: | http://europepmc.org/articles/PMC4830580?pdf=render |