Maximum-Entropy Models of Sequenced Immune Repertoires Predict Antigen-Antibody Affinity.

The immune system has developed a number of distinct complex mechanisms to shape and control the antibody repertoire. One of these mechanisms, the affinity maturation process, works in an evolutionary-like fashion: after binding to a foreign molecule, the antibody-producing B-cells exhibit a high-fr...

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Príomhchruthaitheoirí: Lorenzo Asti, Guido Uguzzoni, Paolo Marcatili, Andrea Pagnani
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2016-04-01
Sraith:PLoS Computational Biology
Rochtain ar líne:http://europepmc.org/articles/PMC4830580?pdf=render