Maximum-Entropy Models of Sequenced Immune Repertoires Predict Antigen-Antibody Affinity.
The immune system has developed a number of distinct complex mechanisms to shape and control the antibody repertoire. One of these mechanisms, the affinity maturation process, works in an evolutionary-like fashion: after binding to a foreign molecule, the antibody-producing B-cells exhibit a high-fr...
| Main Authors: | , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Public Library of Science (PLoS)
2016-04-01
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| 叢編: | PLoS Computational Biology |
| 在線閱讀: | http://europepmc.org/articles/PMC4830580?pdf=render |