Genetic Alterations in Intervertebral Disc Disease

Genetic Alterations in Intervertebral Disc Disease

Background: Intervertebral disc degeneration (IVDD) is considered a multifactorial disease. The last two decades of research strongly demonstrate that genetic factors contribute about 75% of the IVDD etiology. Recent total genome sequencing studies have shed light on the various single nucleotide po...

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Bibliographic Details
Main Authors: Nikolay L. Martirosyan, Arpan A. Patel, Alessandro Carotenuto, M. Yashar S. Kalani, Evgenii Belykh, Corey T. Walker, Mark C. Preul, Nicholas Theodore
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Surgery
Subjects:
Back Pain
Gene Expression
biomarker
degeneration
Disc
Online Access:http://journal.frontiersin.org/Journal/10.3389/fsurg.2016.00059/full

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