Molecular Basis of Broad Spectrum N‑Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2

Bibliographic Details
Main Authors: Erik H. Klontz, Beatriz Trastoy, Daniel Deredge, James K. Fields, Chao Li, Jared Orwenyo, Alberto Marina, Robert Beadenkopf, Sebastian Günther, Jair Flores, Patrick L. Wintrode, Lai-Xi Wang, Marcelo E. Guerin, Eric J. Sundberg
Format: Article
Language:English
Published: American Chemical Society 2019-02-01
Series:ACS Central Science
Online Access:https://doi.org/10.1021/acscentsci.8b00917
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author Erik H. Klontz
Beatriz Trastoy
Daniel Deredge
James K. Fields
Chao Li
Jared Orwenyo
Alberto Marina
Robert Beadenkopf
Sebastian Günther
Jair Flores
Patrick L. Wintrode
Lai-Xi Wang
Marcelo E. Guerin
Eric J. Sundberg
author_facet Erik H. Klontz
Beatriz Trastoy
Daniel Deredge
James K. Fields
Chao Li
Jared Orwenyo
Alberto Marina
Robert Beadenkopf
Sebastian Günther
Jair Flores
Patrick L. Wintrode
Lai-Xi Wang
Marcelo E. Guerin
Eric J. Sundberg
author_sort Erik H. Klontz
collection DOAJ
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institution Directory Open Access Journal
issn 2374-7951
language English
last_indexed 2024-12-14T17:04:35Z
publishDate 2019-02-01
publisher American Chemical Society
record_format Article
series ACS Central Science
spelling doaj.art-004711398bcc42978684ed40020eff2d2022-12-21T22:53:45ZengAmerican Chemical SocietyACS Central Science2374-79512019-02-015352453810.1021/acscentsci.8b00917Molecular Basis of Broad Spectrum N‑Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2Erik H. Klontz0Beatriz Trastoy1Daniel Deredge2James K. Fields3Chao Li4Jared Orwenyo5Alberto Marina6Robert Beadenkopf7Sebastian Günther8Jair Flores9Patrick L. Wintrode10Lai-Xi Wang11Marcelo E. Guerin12Eric J. Sundberg13†Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United StatesStructural Biology Unit, CIC bioGUNE, Derio, SpainDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, United States†Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United StatesDepartment of Chemistry and Biochemistry, University of Maryland, College Park, Maryland, United StatesDepartment of Chemistry and Biochemistry, University of Maryland, College Park, Maryland, United StatesStructural Biology Unit, CIC bioGUNE, Derio, Spain†Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United States†Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United States†Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United StatesDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, United StatesDepartment of Chemistry and Biochemistry, University of Maryland, College Park, Maryland, United StatesStructural Biology Unit, CIC bioGUNE, Derio, Spain†Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United Stateshttps://doi.org/10.1021/acscentsci.8b00917
spellingShingle Erik H. Klontz
Beatriz Trastoy
Daniel Deredge
James K. Fields
Chao Li
Jared Orwenyo
Alberto Marina
Robert Beadenkopf
Sebastian Günther
Jair Flores
Patrick L. Wintrode
Lai-Xi Wang
Marcelo E. Guerin
Eric J. Sundberg
Molecular Basis of Broad Spectrum N‑Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2
ACS Central Science
title Molecular Basis of Broad Spectrum N‑Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2
title_full Molecular Basis of Broad Spectrum N‑Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2
title_fullStr Molecular Basis of Broad Spectrum N‑Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2
title_full_unstemmed Molecular Basis of Broad Spectrum N‑Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2
title_short Molecular Basis of Broad Spectrum N‑Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2
title_sort molecular basis of broad spectrum n glycan specificity and processing of therapeutic igg monoclonal antibodies by endoglycosidase s2
url https://doi.org/10.1021/acscentsci.8b00917
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