The strategy of extrahepatic organs management in early period after adult liver transplantation
With the improvements in surgical technique, the indications for liver transplantation(LT) are being expanded to more complex and severe patients, who not only have liver function in the terminal stage, but also extrahepatic organs involve of varying degrees dysfunction. It was demonstrated that the...
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Format: | Article |
Language: | zho |
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Editorial Office of Journal of Surgery Concepts & Practice
2023-09-01
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Series: | Waike lilun yu shijian |
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Online Access: | https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1704363172711-2014508081.pdf |
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author | DENG Yuxiao, ZHAO Xianyuan, GAO Yuan |
author_facet | DENG Yuxiao, ZHAO Xianyuan, GAO Yuan |
author_sort | DENG Yuxiao, ZHAO Xianyuan, GAO Yuan |
collection | DOAJ |
description | With the improvements in surgical technique, the indications for liver transplantation(LT) are being expanded to more complex and severe patients, who not only have liver function in the terminal stage, but also extrahepatic organs involve of varying degrees dysfunction. It was demonstrated that the strategy of extrahepatic organs management in early period after LT was associated with improving recovery. This paper summarized the strategy of extrahepatic organs management in early period after adult LT. Continuing to monitor system hemodynamics is helpful for stable graft perfusion. It is necessary to manage derangements of preload, myocardial contractility, and afterload. Early postoperative extubation is recommended by current guidelines. Routine screening pulmonary complications may help weaning from the ventilator. The diagnosis of acute kidney injury(AKI) after LT has been reported to using Kidney Disease: Improving Global Outcomes(KDIGO) criteria, a delayed calcineurin inhibitor initiation strategy may be beneficial for renal protection. Currently, there is no consensus on timing of renal replacement therapy initiation in patients with AKI. Patients with cirrhosis and a history of hepatic encephalopathy(HE) displays impaired neurological recovery, the diagnosis of HE is crucial and challenging. |
first_indexed | 2024-03-08T16:40:43Z |
format | Article |
id | doaj.art-004923bb36cb4cb3af3a5acff277ef4c |
institution | Directory Open Access Journal |
issn | 1007-9610 |
language | zho |
last_indexed | 2024-03-08T16:40:43Z |
publishDate | 2023-09-01 |
publisher | Editorial Office of Journal of Surgery Concepts & Practice |
record_format | Article |
series | Waike lilun yu shijian |
spelling | doaj.art-004923bb36cb4cb3af3a5acff277ef4c2024-01-05T09:51:37ZzhoEditorial Office of Journal of Surgery Concepts & PracticeWaike lilun yu shijian1007-96102023-09-01280541541910.16139/j.1007-9610.2023.05.04The strategy of extrahepatic organs management in early period after adult liver transplantationDENG Yuxiao, ZHAO Xianyuan, GAO Yuan0Department of Critical Care Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, ChinaWith the improvements in surgical technique, the indications for liver transplantation(LT) are being expanded to more complex and severe patients, who not only have liver function in the terminal stage, but also extrahepatic organs involve of varying degrees dysfunction. It was demonstrated that the strategy of extrahepatic organs management in early period after LT was associated with improving recovery. This paper summarized the strategy of extrahepatic organs management in early period after adult LT. Continuing to monitor system hemodynamics is helpful for stable graft perfusion. It is necessary to manage derangements of preload, myocardial contractility, and afterload. Early postoperative extubation is recommended by current guidelines. Routine screening pulmonary complications may help weaning from the ventilator. The diagnosis of acute kidney injury(AKI) after LT has been reported to using Kidney Disease: Improving Global Outcomes(KDIGO) criteria, a delayed calcineurin inhibitor initiation strategy may be beneficial for renal protection. Currently, there is no consensus on timing of renal replacement therapy initiation in patients with AKI. Patients with cirrhosis and a history of hepatic encephalopathy(HE) displays impaired neurological recovery, the diagnosis of HE is crucial and challenging.https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1704363172711-2014508081.pdf|liver transplantation|extrahepatic organ|intensive care |
spellingShingle | DENG Yuxiao, ZHAO Xianyuan, GAO Yuan The strategy of extrahepatic organs management in early period after adult liver transplantation Waike lilun yu shijian |liver transplantation|extrahepatic organ|intensive care |
title | The strategy of extrahepatic organs management in early period after adult liver transplantation |
title_full | The strategy of extrahepatic organs management in early period after adult liver transplantation |
title_fullStr | The strategy of extrahepatic organs management in early period after adult liver transplantation |
title_full_unstemmed | The strategy of extrahepatic organs management in early period after adult liver transplantation |
title_short | The strategy of extrahepatic organs management in early period after adult liver transplantation |
title_sort | strategy of extrahepatic organs management in early period after adult liver transplantation |
topic | |liver transplantation|extrahepatic organ|intensive care |
url | https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1704363172711-2014508081.pdf |
work_keys_str_mv | AT dengyuxiaozhaoxianyuangaoyuan thestrategyofextrahepaticorgansmanagementinearlyperiodafteradultlivertransplantation AT dengyuxiaozhaoxianyuangaoyuan strategyofextrahepaticorgansmanagementinearlyperiodafteradultlivertransplantation |