Differences in Genetic Background Contribute to Pseudomonas Exotoxin A-Induced Hepatotoxicity in Rats

Differences in Genetic Background Contribute to Pseudomonas Exotoxin A-Induced Hepatotoxicity in Rats

Pseudomonas aeruginosa exotoxin A (PEA) causes severe hepatotoxicity in experimental animals and is useful in investigations of immune-mediated liver injury. However, strain differences in the sensitivity to PEA-induced hepatotoxicity in rats remains be elucidated. In this study, we determined the s...

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Bibliographic Details
Main Authors:	Chien-Chao Chiu, Yu-Chih Wang, Wen-Ching Huang, Yi-Hsun Chen, Shao-Wen Hung, Yen-Te Huang, Hsiao-Li Chuang, Yi-Chih Chang
Format:	Article
Language:	English
Published:	MDPI AG 2017-07-01
Series:	Toxins
Subjects:	Pseudomonas exotoxin A genetic background hepatotoxicity massive necrosis
Online Access:	https://www.mdpi.com/2072-6651/9/7/224

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